Genetic Aspects of Glaucoma: An Updated Review
Por:
Chacon-Camacho O.F., Arce-Gonzalez R., Sánchez-De la Rosa F., Urióstegui-Rojas A., Hofmann-Blancas M.E., Mata-Flores F., Zenteno J.C.
Publicada:
1 ene 2024
Resumen:
Glaucoma is a group of diverse diseases characterized by cupping of the optic nerve head due to the loss of retinal ganglion cells. It is the most common cause of irreversible blindness throughout the world; therefore, its timely diagnosis and early detection through an ophthalmological examination are very important. We, herein, present the information on the epidemiology, pathophysiology, clinical diagnosis, and treatment of glaucoma. We also emphasize the investigations of the last decades that have allowed identifying numerous genes and susceptibility genetic factors. We have also described in detail the genes whose mutations cause or contribute to the development of the disease. © 2024 Bentham Science Publishers.
Filiaciones:
Department of Genetics, Institute of Ophthalmology “Conde de Valenciana”, Mexico
Laboratorio 5 Edificio A-4, Carrera de Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Mexico City, Mexico
Department of Integral Ophthalmology, Institute of Ophthalmology “Conde de Valenciana”, Mexico City, Mexico
Department of Glaucoma, Institute of Ophthalmology “Conde de Valenciana”, Mexico
Biochemistry Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico
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