Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Por:
Naghavi M., Ong K.L., Aali A., Ababneh H.S., Abate Y.H., Abbafati C., Abbasgholizadeh R., Abbasian M., Abbasi-Kangevari M., Abbastabar H., Abd ElHafeez S., Abdelmasseh M., Abd-Elsalam S., Abdelwahab A., Abdollahi M., Abdollahifar M.-A., Abdoun M., Abdulah D.M., Abdullahi A., Abebe M., Abebe S.S., Abedi A., Abegaz K.H., Abhilash E.S., Abidi H., Abiodun O., Aboagye R.G., Abolhassani H., Abolmaali M., Abouzid M., Aboye G.B., Abreu L.G., Abrha W.A., Abtahi D., Abu Rumeileh S., Abualruz H., Abubakar B., Abu-Gharbieh E., Abu-Rmeileh N.M., Aburuz S., Abu-Zaid A., Accrombessi M.M.K., Adal T.G., Adamu A.A., Addo I.Y., Addolorato G., Adebiyi A.O., Adekanmbi V., Adepoju A.V., Adetunji C.O., Adetunji J.B., Adeyeoluwa T.E., Adeyinka D.A., Adeyomoye O.I., Admass B.A., Adnani Q.E.S., Adra S., Afolabi A.A., Afzal M.S., Afzal S., Agampodi S.B., Agasthi P., Aggarwal M., Aghamiri S., Agide F.D., Agodi A., Agrawal A., Agyemang-Duah W., Ahinkorah B.O., Ahmad A., Ahmad D., Ahmad F., Ahmad M.M., Ahmad S., Ahmad T., Ahmadi K., Ahmadzade A.M., Ahmed A., Ahmed H., Ahmed L.A., Ahmed M.S., Ahmed M.B., Ahmed S.A., Ajami M., Aji B., Akara E.M., Akbarialiabad H., Akinosoglou K., Akinyemiju T., Akkaif M.A., Akyirem S., Al Hamad H., Al Hasan S.M., Alahdab F., Alalalmeh S.O., Alalwan T.A., Al-Aly Z., Alam K., Alam M., Alam N., Al-Amer R.M., Alanezi F.M., Alanzi T.M., Al-Azzam S., Albakri A., Albashtawy M., AlBataineh M.T., Alcalde-Rabanal J.E., Aldawsari K.A., Aldhaleei W.A., Aldridge R.W., Alema H.B., Alemayohu M.A., Alemi S., Alemu Y.M., Al-Gheethi A.A.S., Alhabib K.F., Alhalaiqa F.A.N., Al-Hanawi M.K., Ali A., Ali L., Ali M.U., Ali R., Ali S., Ali S.S.S., Alicandro G., Alif S.M., Alikhani R., Alimohamadi Y., Aliyi A.A., Aljasir M.A.M., Aljunid S.M., Alla F., Allebeck P., Al-Marwani S., Al-Maweri S.A.A., Almazan J.U., Al-Mekhlafi H.M., Almidani L., Almidani O., Alomari M.A., Al-Omari B., Alonso J., Alqahtani J.S., Alqalyoobi S., Alqutaibi A.Y., Al-Sabah S.K., Altaany Z., Altaf A., Al-Tawfiq J.A., Altirkawi K.A., Aluh D.O., Alvis-Guzman N., Alwafi H., Al-Worafi Y.M., Aly H., Aly S., Alzoubi K.H., Amani R., Amare A.T., Amegbor P.M., Ameyaw E.K., Amin T.T., Amindarolzarbi A., Amiri S., Amirzade-Iranaq M.H., Amu H., Amugsi D.A., Amusa G.A., Ancuceanu R., Anderlini D., Anderson D.B., Andrade P.P., Andrei C.L., Andrei T., Angus C., Anil A., Anil S., Anoushiravani A., Ansari H., Ansariadi A., Ansari-Moghaddam A., Antony C.M., Antriyandarti E., Anvari D., Anvari S., Anwar S., Anwar S.L., Anwer R., Anyasodor A.E., Aqeel M., Arab J.P., Arabloo J., Arafat M., Aravkin A.Y., Areda D., Aremu A., Aremu O., Ariffin H., Arkew M., Armocida B., Arndt M.B., Arnlov J., Arooj M., Artamonov A.A., Arulappan J., Aruleba R.T., Arumugam A., Asaad M., Asadi-Lari M., Asgedom A.A., Asghariahmadabad M., Asghari-Jafarabadi M., Ashraf M., Aslani A., Astell-Burt T., Athar M., Athari S.S., Atinafu B.T.T., Atlaw H.W., Atorkey P., Atout M.M.W., Atreya A., Aujayeb A., Ausloos M., Avan A., Awedew A.F., Aweke A.M., Ayala Quintanilla B.P.A., Ayatollahi H., Ayuso-Mateos J.L., Ayyoubzadeh S.M., Azadnajafabad S., Azevedo R.M.S., Azzam A.Y., Darshan B.B., Babu A.S., Badar M., Badiye A.D., Baghdadi S., Bagheri N., Bagherieh S., Bah S., Bahadorikhalili S., Bahmanziari N., Bai R., Baig A.A., Baker J.L., Bako A.T., Bakshi R.K., Balakrishnan S., Balasubramanian M., Baltatu O.C., Bam K., Banach M., Bandyopadhyay S., Banik P.C., Bansal H., Bansal K., Barbic F., Barchitta M., Bardhan M., Bardideh E., Barker-Collo S.L., Barnighausen T.W., Barone-Adesi F., Barqawi H.J., Barrero L.H., Barrow A., Barteit S., Barua L., Basharat Z., Bashiri A., Basiru A., Baskaran P., Basnyat B., Bassat Q., Basso J.D., Basting A.V.L., Basu S., Batra K., Baune B.T., Bayati M., Bayileyegn N.S., Beaney T., Bedi N., Beghi M., Behboudi E., Behera P., Behnoush A.H., Behzadifar M., Beiranvand M., Bejarano Ramirez D.F., Béjot Y., Belay S.A., Belete C.M., Bell M.L., Bello M.B., Bello O.O., Belo L., Beloukas A., Bender R.G., Bensenor I.M., Beran A., Berezvai Z., Berhie A.Y., Berice B.N., Bernstein R.S., Bertolacci G.J., Bettencourt P.J.G., Beyene K.A., Bhagat D.S., Bhagavathula A.S., Bhala N., Bhalla A., Bhandari D., Bhangdia K., Bhardwaj N., Bhardwaj P., Bhardwaj P.V., Bhargava A., Bhaskar S., Bhat V., Bhatti G.K., Bhatti J.S., Bhatti M.S., Bhatti R., Bhutta Z.A., Bikbov B., Bishai J.D., Bisignano C., Bisulli F., Biswas A., Biswas B., Bitaraf S., Bitew B.D., Bitra V.R., Bjørge T., Boachie M.K., Boampong M.S., Bobirca A.V., Bodolica V., Bodunrin A.O., Bogale E.K., Bogale K.A., Bohlouli S., Bolarinwa O.A., Boloor A., Bonakdar Hashemi M.B., Bonny A., Bora K., Bora Basara B., Borhany H., Borzutzky A., Bouaoud S., Boustany A., Boxe C., Boyko E.J., Brady O.J., Braithwaite D., Brant L.C., Brauer M., Brazinova A., Brazo-Sayavera J., Breitborde N.J.K., Breitner S., Brenner H., Briko A.N., Briko N.I., Britton G., Brown J., Brugha T., Bulamu N.B., Bulto L.N., Buonsenso D., Burns R.A., Busse R., Bustanji Y., Butt N.S., Butt Z.A., Caetano dos Santos F.L., Calina D., Camera L.A., Campos L.A., Campos-Nonato I.R., Cao C., Cao Y., Capodici A., Cárdenas R., Carr S., Carreras G., Carrero J.J., Carugno A., Carvalheiro C.G., Carvalho F., Carvalho M., Castaldelli-Maia J.M., Castañeda-Orjuela C.A., Castelpietra G., Catalá-López F., Catapano A.L., Cattaruzza M.S., Cederroth C.R., Cegolon L., Cembranel F., Cenderadewi M., Cercy K.M., Cerin E., Cevik M., Chadwick J., Chahine Y., Chakraborty C., Chakraborty P.A., Chan J.S.K., Chan R.N.C., Chandika R.M., Chandrasekar E.K., Chang C.-K., Chang J.-C., Chanie G.S., Charalampous P., Chattu V.K., Chaturvedi P., Chatzimavridou-Grigoriadou V., Chaurasia A., Chen A.W., Chen A.-T., Chen C.S., Chen H., Chen M.X., Chen S., Cheng C.-Y., Cheng E.T.W., Cherbuin N., Cheru W.A., Chien J.-H., Chimed-Ochir O., Chimoriya R., Ching P.R., Chirinos-Caceres J.L., Chitheer A., Cho W.C.S., Chong B., Chopra H., Choudhari S.G., Chowdhury R., Christopher D.J., Chukwu I.S., Chung E., Chung S.-C., Chutiyami M., Cindi Z., Cioffi I., Claassens M.M., Claro R.M., Coberly K., Cogen R.M., Columbus A., Comfort H., Conde J., Cortese S., Cortesi P.A., Costa V.M., Costanzo S., Cousin E., Couto R.A.S., Cowden R.G., Cramer K.M., Criqui M.H., Cruz-Martins N., Cuadra-Hernandez S.M., Culbreth G.T., Cullen P., Cunningham M., Curado M.P., Dadana S., Dadras O., Dai S., Dai X., Dai Z., Dalli L.L., Damiani G., Darega Gela J., Das J.K., Das S., Dascalu A.M., Dash N.R., Dashti M., Dastiridou A., Davey G., Davila-Cervantes C.A., Davis Weaver N., Davletov K., De Leo D., de Luca K., Debele A.T., Debopadhaya S., Degenhardt L., Dehghan A., Deitesfeld L., Del Bo C., Delgado-Enciso I., Demessa B.H., Demetriades A.K., Deng K., Deng X., Denova-Gutierrez E., Deravi N., Dereje N., Dervenis N., Derviševic E., Des Jarlais D.C., Desai H.D., Desai R., Devanbu V.G.C., Dewan S.M.R., Dhali A., Dhama K., Dhimal M., Dhingra S., Dhulipala V.R., Dias da Silva D., Diaz D., Diaz M.J., Dima A., Ding D.D., Ding H., Dinis-Oliveira R.J., Dirac M.A., Djalalinia S., Do T.H.P., do Prado C.B., Doaei S., Dodangeh M., Dohare S., Dokova K.G., Dolecek C., Dominguez R.M.V., Dong W., Dongarwar D., D'Oria M., Dorostkar F., Dorsey E.R., dos Santos W.M., Doshi R., Doshmangir L., Dowou R.K., Driscoll T.R., Dsouza H.L., Dsouza V., Du M., Dube J., Duncan B.B., Duraes A.R., Duraisamy S., Durojaiye O.C., Dwyer-Lindgren L., Dzianach P.A., Dziedzic A.M., E'Mar A.R., Eboreime E., Ebrahimi A., Echieh C.P., Edinur H.A., Edvardsson D., Edvardsson K., Efendi D., Efendi F., Effendi D.E., Eikemo T.A., Eini E., Ekholuenetale M., Ekundayo T.C., El Sayed I., Elbarazi I., Elema T.B., Elemam N.M., Elgar F.J., Elgendy I.Y., ElGohary G.M.T., Elhabashy H.R., Elhadi M., El-Huneidi W., Elilo L.T., Elmeligy O.A.A., Elmonem M.A., Elshaer M., Elsohaby I., Emeto T.I., Engelbert Bain L., Erkhembayar R., Esezobor C.I., Eshrati B., Eskandarieh S., Espinosa-Montero J., Esubalew H., Etaee F., Fabin N., Fadaka A.O., Fagbamigbe A.F., Fahim A., Fahimi S., Fakhri-Demeshghieh A., Falzone L., Fareed M., Sa Farinha C.S.E., Faris M.E.M., Faris P.S., Faro A., Fasanmi A.O., Fatehizadeh A., Fattahi H., Fauk N.K., Fazeli P., Feigin V.L., Feizkhah A., Fekadu G., Feng X., Fereshtehnejad S.-M., Feroze A.H., Ferrante D., Ferrari A.J., Ferreira N., Fetensa G., Feyisa B.R., Filip I., Fischer F., Flavel J., Flood D., Florin B.T., Foigt N.A., Folayan M.O., Fomenkov A.A., Foroutan B., Foroutan M., Forthun I., Fortuna D., Foschi M., Fowobaje K.R., Francis K.L., Franklin R.C., Freitas A., Friedman J., Friedman S.D., Fukumoto T., Fuller J.E., Fux B., Gaal P.A., Gadanya M.A., Gaidhane A.M., Gaihre S., Gakidou E., Galali Y., Galles N.C., Gallus S., Ganbat M., Gandhi A.P., Ganesan B., Ganiyani M.A., Garcia-Gordillo M., Gardner W.M., Garg J., Garg N., Gautam R.K., Gbadamosi S.O., Gebi T.G., Gebregergis M.W., Gebrehiwot M., Gebremeskel T.G., Georgescu S.R., Getachew T., Gething P.W., Getie M., Ghadiri K., Ghahramani S., Ghailan K.Y., Ghasemi M.-R., Ghasempour Dabaghi G., Ghasemzadeh A., Ghashghaee A., Ghassemi F., Ghazy R.M., Ghimire A., Ghoba S., Gholamalizadeh M., Gholamian A., Gholamrezanezhad A., Gholizadeh N., Ghorbani M., Ghorbani Vajargah P., Ghoshal A.G., Gill P.S., Gill T.K., Gillum R.F., Ginindza T.G., Girmay A., Glasbey J.C., Gnedovskaya E.V., Gobolos L., Godinho M.A., Goel A., Golchin A., Goldust M., Golechha M., Goleij P., Gomes N.G.M., Gona P.N., Gopalani S.V., Gorini G., Goudarzi H., Goulart A.C., Goulart B.N.G., Goyal A., Grada A., Graham S.M., Grivna M., Grosso G., Guan S.-Y., Guarducci G., Gubari M.I.M., Gudeta M.D., Guha A., Guicciardi S., Guimaraes R.A., Gulati S., Gunawardane D.A., Gunturu S., Guo C., Gupta A.K., Gupta B., Gupta M.K., Gupta M., Gupta R.D., Gupta R., Gupta S., Gupta V.B., Gupta V.K., Gurmessa L., Gutierrez R.A., Habibzadeh F., Habibzadeh P., Haddadi R., Hadei M., Hadi N.R., Haep N., Hafezi-Nejad N., Haile D., Hailu A., Haj-Mirzaian A., Halboub E.S., Hall B.J., Haller S., Halwani R., Hamadeh R.R., Hameed S., Hamidi S., Hamilton E.B., Han C., Han Q., Hanif A., Hanifi N., Hankey G.J., Hanna F., Hannan M.A., Haque M.N., Harapan H., Hargono A., Haro J.M., Hasaballah A.I., Hasan I., Hasan M.T., Hasani H., Hasanian M., Hashi A., Hasnain M.S., Hassan I., Hassanipour S., Hassankhani H., Haubold J., Havmoeller R.J., Hay S.I., He J., Hebert J.J., Hegazi O.E., Heidari G., Heidari M., Heidari-Foroozan M., Helfer B., Hendrie D., Herrera-Serna B.Y., Herteliu C., Hesami H., Hezam K., Hill C.L., Hiraike Y., Holla R., Horita N., Hossain M.M., Hossain S., Hosseini M.-S., Hosseinzadeh H., Hosseinzadeh M., Hosseinzadeh Adli A.H., Hostiuc M., Hostiuc S., Hsairi M., Chiarong Hsieh V., Hsu R.L., Hu C., Huang J., Hultstrom M., Humayun A., Hundie T.G., Hussain J., Azhar Hussain M., Hussein N.R., Hussien F.M., Huynh H.-H., Hwang B.-F., Ibitoye S.E., Ibrahim K.S., Iftikhar P.M., Ijo D., Ikiroma A.I., Ikuta K.S., Ikwegbue P.C., Ilesanmi O.S., Ilic I.M., Ilic M.D., Imam M.T., Immurana M., Inamdar S., Indriasih E., Iqhrammullah M., Iradukunda A., Iregbu K.C., Islam M.R., Islam S.M.S., Islami F., Ismail F., Ismail N.E., Iso H., Isola G., Iwagami M., Iwu C.C.D., Iyamu I.O., Iyer M., Linda Merin J., Jaafari J., Jacob L., Jacobsen K.H., Jadidi-Niaragh F., Jafarinia M., Jafarzadeh A., Jaggi K., Jahankhani K., Jahanmehr N., Jahrami H., Jain N., Jairoun A.A., Jaiswal A., Jamshidi E., Janko M.M., Jatau A.I., Javadov S., Javaheri T., Jayapal S.K., Jayaram S., Jebai R., Jee S.H., Jeganathan J., Jha A.K., Jha R.P., Jiang H., Jin Y., Johnson O., Jokar M., Jonas J.B., Joo T., Joseph A., Joseph N., Joshua C.E., Joshy G., Jozwiak J.J., Jurisson M., Vaishali K., Kaambwa B., Kabir A., Kabir Z., Kadashetti V., Kadir D.H., Kalani R., Kalankesh L.R., Kaliyadan F., Kalra S., Kamal V.K., Kamarajah S.K., Kamath R., Kamiab Z., Kamyari N., Kanagasabai T., Kanchan T., Kandel H., Kanmanthareddy A.R., Kanmiki E.W., Kanmodi K.K., Suthanthira Kannan S., Kansal S.K., Kantar R.S., Kapoor N., Karajizadeh M., Karanth S.D., Karasneh R.A., Karaye I.M., Karch A., Karim A., Karimi S.E., Karimi Behnagh A., Kashoo F.Z., Kasnazani Q.H.A., Kasraei H., Kassebaum N.J., Kassel M.B., Kauppila J.H., Kaur N., Kawakami N., Kayode G.A., Kazemi F., Kazemian S., Kazmi T.H., Kebebew G.M., Kebede A.D., Kebede F., Keflie T.S., Keiyoro P.N., Keller C., Kelly J.T., Kempen J.H., Kerr J.A., Kesse-Guyot E., Khajuria H., Khalaji A., Khalid N., Khalil A.A., Khalilian A., Khamesipour F., Khan A., Khan G., Khan I., Khan I.A., Khan M.N., Khan M., Khan M.J., Khan M.A., Khan Z.A., Khan Suheb M.Z.
Publicada:
1 ene 2024
Ahead of Print:
1 may 2024
Categoría:
Medicine (miscellaneous)
Resumen:
Background: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. Methods: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model—a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates—with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality—which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. Findings: The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2–100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1–290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1–211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4–48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3–37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7–9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. Interpretation: Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving in
Filiaciones:
Naghavi M.:
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
School of Medicine, University of Washington, Seattle, WA, United States
Ong K.L.:
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
Aali A.:
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Ababneh H.S.:
Radiation Oncology, Massachusetts General Hospital, Boston, MA, United States
Abate Y.H.:
Department of Clinical Governance and Quality Improvement, Aleta Wondo Hospital, Aleta Wondo, Ethiopia
Abbafati C.:
Department of Juridical and Economic Studies, La Sapienza University, Rome, Italy
Abbasgholizadeh R.:
Doheny Eye Institute, University of California Los Angeles, Los Angeles, CA, United States
Abbasian M.:
Department of Orthopedic Surgery, Harvard University, Boston, MA, United States
Department of Orthopaedic Surgery, Tehran, Iran
Tehran, Iran
Abbasi-Kangevari M.:
Tehran, Iran
Non-communicable Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran
Abbastabar H.:
Tehran, Iran
Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Abd ElHafeez S.:
Department of Epidemiology, Alexandria University, Alexandria, Egypt
Abdelmasseh M.:
Department of Surgery, Marshall University, Huntington, WV, United States
Abd-Elsalam S.:
Department of Tropical Medicine and Infectious Diseases, Tanta University, Tanta, Egypt
Abdelwahab A.:
Department of Internal Medicine, Baylor College of Medicine, Houston, TX, United States
Abdollahi M.:
Tehran, Iran
The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran
School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
Abdollahifar M.-A.:
Department of Small Animal Clinical Sciences, University of Saskatchewan, Saskatoon, SK, Canada
Abdoun M.:
Department of Medicine, University of Setif Algeria, Sétif, Algeria
Abdulah D.M.:
Community and Maternity Nursing Unit, University of Duhok, Duhok, Iraq
Abdullahi A.:
Department of Physiotherapy, Bayero University Kano, Kano, Nigeria
Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hong Kong
Abebe M.:
Department of Midwifery, Dilla University, Dilla, Ethiopia
Abebe S.S.:
Department of Public Health, Haramaya University, Harar, Ethiopia
Abedi A.:
Department of Neurosurgery, University of Southern California, Los Angeles, CA, United States
Keck School of Medicine, University of Southern California, Los Angeles, CA, United States
Abegaz K.H.:
Department of Biostatistics, Near East University, TRNC, Nicosia, Cyprus
Department of Biostatistics and Health Informatics, Madda Walabu University, Bale Robe, Ethiopia
Abhilash E.S.:
Department of Botany, Sree Narayana Guru College Chelannur, Kozhikode, India
Abidi H.:
Laboratory Technology Sciences Department, Yasuj University of Medical Sciences, Yasuj, Iran
Abiodun O.:
Department of Community Medicine, Babcock University, Ilishan-Remo, Nigeria
Aboagye R.G.:
Department of Family and Community Health, University of Health and Allied Sciences, Ho, Ghana
Abolhassani H.:
Tehran, Iran
Research Center for Immunodeficiencies, Tehran University of Medical Sciences, Tehran, Iran
Department of Medical Biochemistry and Biophysics, Shefa Neuroscience Research Center, Tehran, Iran
Abolmaali M.:
Tehran, Iran
Department of Neurosurgery, Shefa Neuroscience Research Center, Tehran, Iran
Khatam Al-anbia Hospital, Shefa Neuroscience Research Center, Tehran, Iran
Abouzid M.:
Department of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Poznan, Poland
Aboye G.B.:
Department of Public Health, Madda Walabu University, Addis Ababa, Ethiopia
Department of Nutrition and Dietetics, Jimma University, Addis Ababa, Ethiopia
Abreu L.G.:
Department of Pediatric Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil
Abrha W.A.:
Department of Adult Health Nursing, Aksum University, Aksum, Ethiopia
Abtahi D.:
Department of Anesthesiology, Tehran, Iran
Tehran, Iran
Abu Rumeileh S.:
Department of Neurology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany
Abualruz H.:
Department of Nursing, Al Zaytoonah University of Jordan, Amman, Jordan
Abubakar B.:
Department of Pharmacology and Toxicology, Usmanu Danfodiyo University, Sokoto, Sokoto, Nigeria
Nigerian Institute of Medical Research, Lagos, Nigeria
Abu-Gharbieh E.:
Clinical Sciences Department, Sharjah, United Arab Emirates
Abu-Rmeileh N.M.:
Institute of Community and Public Health, Birzeit University, Ramallah, Palestine
Aburuz S.:
College of Pharmacy, University of Jordan, Amman, Jordan
Abu-Zaid A.:
Department of Surgery, Alfaisal University, Riyadh, Saudi Arabia
College of Graduate Health Sciences, University of Tennessee, Memphis, TN, United States
Accrombessi M.M.K.:
Department of Disease Control, London School of Hygiene & Tropical Medicine, London, United Kingdom
Department of Clinical Research, Clinical Research Institute of Benin (IRCB), Abomey-Calavi, Benin
Adal T.G.:
Department of Public Health, Wolkite University, Wolkite, Ethiopia
Adamu A.A.:
Department of Global Health, Stellenbosch University, Cape Town, South Africa
Cochrane South Africa, Cape Town, South Africa
Addo I.Y.:
Centre for Social Research in Health, University of New South Wales, Sydney, NSW, Australia
Quality and Systems Performance Unit, Cancer Institute NSW, Sydney, NSW, Australia
Addolorato G.:
Internal Medicine and Alcohol Related Disease Unit, Fondazione Policlinico Universitario A Gemelli IRCCS (Agostino Gemelli University Polyclinic IRCCS), Rome, Italy
Department of Medical and Surgical Sciences, Universita Cattolica di Roma (Catholic University of Rome), Rome, Italy
Adebiyi A.O.:
Department of Community Medicine, University of Ibadan, Ibadan, Nigeria
Department of Community Medicine, University College Hospital, Ibadan, Ibadan, Nigeria
Adekanmbi V.:
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, United States
Adepoju A.V.:
Department of HIV and Infectious Diseases, Jhpiego, Abuja, Nigeria
Department of Adolescent Research and Care, Adolescent Friendly Research Initiative and Care, Ado Ekiti, Nigeria
Adetunji C.O.:
Department of Microbiology, Edo State University Uzairue, Iyamho, Nigeria
Adetunji J.B.:
Department of Biochemistry, Osun State University, Osogbo, Nigeria
Adeyeoluwa T.E.:
Department of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria
Department of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Ondo, Nigeria
Adeyinka D.A.:
Department of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, SK, Canada
Department of Public Health, Federal Ministry of Health, Abuja, Nigeria
Adeyomoye O.I.:
Department of Physiology, University of Medical Sciences, Ondo, Ondo, Nigeria
Admass B.A.:
University of Gondar, Gondar, Ethiopia
Adnani Q.E.S.:
Faculty of Medicine, Universitas Padjadjaran (Padjadjaran University), Bandung, Indonesia
Adra S.:
Clinical Sciences Department, Sharjah, United Arab Emirates
Afolabi A.A.:
Department of Community Medicine, University of Ibadan, Ibadan, Nigeria
Afzal M.S.:
Department of Life Sciences, University of Management and Technology, Lahore, Pakistan
Afzal S.:
Department of Community Medicine, King Edward Memorial Hospital, Lahore, Pakistan
Department of Public Health, Public Health Institute, Lahore, Pakistan
Agampodi S.B.:
Department of Community Medicine, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka
International Vaccine Institute, Seoul, South Korea
Agasthi P.:
Department of Cardiovascular Medicine, Mayo Clinic, Scottsdale, AZ, United States
Aggarwal M.:
Department of Internal Medicine, Cleveland Clinic, Cleveland, OH, United States
Aghamiri S.:
Department of Biotechnology, Tehran, Iran
Tehran, Iran
Agide F.D.:
Department of Health Education and Health Promotion, Wachemo University, Hossana, Ethiopia
Agodi A.:
Department of Medical and Surgical Sciences and Advanced Technologies, 'GF Ingrassia' University of Catania, Catania, Italy
Agrawal A.:
Section of General Internal Medicine, Baylor College of Medicine, Houston, TX, United States
Trivedi School of Biosciences, Ashoka University, Haryana, Sonipat, 131029, India
Agyemang-Duah W.:
Department of Geography and Planning, Queen's University, Kingston, ON, Canada
Ahinkorah B.O.:
School of Public Health, University of Technology Sydney, Sydney, NSW, Australia
Ahmad A.:
Department of Medical Biochemistry, Shaqra University, Shaqra, Saudi Arabia
Ahmad D.:
School of Medicine and Psychology, Australian National University, Canberra, ACT, Australia
Public Health Foundation of India, Gandhinagar, India
Ahmad F.:
College of Medicine, Sharjah, United Arab Emirates
Ahmad M.M.:
Department of Clinical Nursing, University of Jordan, Amman, Jordan
Ahmad S.:
Department of Health and Biological Sciences, Abasyn University, Peshawar, Pakistan
Department of Natural Sciences, Lebanese American University, Beirut, Lebanon
Ahmad T.:
Department of Epidemiology and Health Statistics, Southeast University, Nanjing, China
Ahmadi K.:
School of Public Health, Imperial College London, London, United Kingdom
Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
Ahmadzade A.M.:
Department of Neuroscience, Mashhad University of Medical Sciences, Mashhad, Iran
Ahmed A.:
Department of Pharmacy Practice, Riphah Institute of Pharmaceutical Sciences, Islamabad, Pakistan
Division of Infectious Diseases and Global Public Health (IDGPH), University of California, San Diego, CA, United States
Ahmed H.:
Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan
Ahmed L.A.:
Institute of Public Health, United Arab Emirates University, Al Ain, United Arab Emirates
Ahmed M.S.:
Department of Pathology and Microbiology, University of Duhok, Duhok, Iraq
Ahmed M.B.:
Department of Epidemiology, Jimma University, Jimma, Ethiopia
Australian Center for Precision Health, University of South Australia, Adelaide, SA, Australia
Ahmed S.A.:
Brody School of Medicine, Greenville, NC, United States
Ajami M.:
National Nutrition and Food Technology Research Institute, Tehran, Iran
Tehran, Iran
Department of Food and Nutrition Policy and Planning Research, National Institute of Nutrition, Tehran, Iran
Aji B.:
Faculty of Medicine and Public Health, Jenderal Soedirman University, Purwokerto, Indonesia
Akara E.M.:
Moyen Mono Health District, Ministry of Health, Tohoun, Togo
Akbarialiabad H.:
St George and Sutherland Clinical School, University of New South Wales, Sydney, NSW, Australia
Akinosoglou K.:
Department of Internal Medicine, University of Patras, Patras, Greece
Department of Internal Medicine and Infectious Diseases, University General Hospital of Patras, Patras, Greece
Akinyemiju T.:
Department of Population Health Sciences, Duke University, Durham, NC, United States
Duke Global Health Institute, Duke University, Durham, NC, United States
Akkaif M.A.:
Department of Cardiology, Fudan University, Shanghai, China
Akyirem S.:
Yale School of Nursing, Yale University, New Haven, CT, United States
Al Hamad H.:
Department of Geriatric and Long Term Care, Hamad Medical Corporation, Doha, Qatar
Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar
Al Hasan S.M.:
Division of Public Health Sciences, Washington University School of Medicine, St Louis, MO, United States
Alahdab F.:
McWilliams School of Biomedical Informatics, UTHealth, Houston, TX, United States
Department of Biomedical Informatics, Biostatistics, and Epidemiology, University of Missouri, Columbia, MO, United States
Alalalmeh S.O.:
Department of Clinical Sciences, Ajman University, Ajman, United Arab Emirates
Alalwan T.A.:
Department of Biology, University of Bahrain, Sakhir, Bahrain
Al-Aly Z.:
John T. Milliken Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO, United States
Clinical Epidemiology Center, US Department of Veterans Affairs (VA), St Louis, MO, United States
Alam K.:
Murdoch Business School, Murdoch University, Perth, WA, Australia
Alam M.:
Department of Bioengineering, George Mason University, Fairfax, VA, United States
Alam N.:
Prevention Division, Queensland Health, Brisbane, QLD, Australia
Centre for Environment and Population Health, Griffith University, Nathan, QLD, Australia
Al-Amer R.M.:
School of Nursing, Yarmouk University, Irbid, Jordan
School of Nursing and Midwifery, Western Sydney University, Sydney, NSW, Australia
Alemu Y.M.:
National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia
Ali M.U.:
Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hong Kong
Alikhani R.:
Tehran, Iran
Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
Alimohamadi Y.:
Tehran, Iran
Pars Advanced and Minimally Invasive Medical Manners Research Center, Shefa Neuroscience Research Center, Tehran, Iran
Allebeck P.:
Tehran, Iran
Department of Global Public Health, Shefa Neuroscience Research Center, Tehran, Iran
Almidani L.:
Doheny Image Reading and Research Lab (DIRRL), University of California Los Angeles, Los Angeles, CA, United States
Alqalyoobi S.:
Department of Internal Medicine, Greenville, NC, United States
Altirkawi K.A.:
University of Sharjah, Sharjah, United Arab Emirates
Aly H.:
Department of Pediatrics, Cleveland Clinic, Cleveland, OH, United States
Aly S.:
Department of Pediatrics, Harvard University, Boston, MA, United States
Alzoubi K.H.:
Department of Pharmacy Practice and Pharmacotherapeutics, Sharjah, United Arab Emirates
Amiri S.:
Tehran, Iran
Amirzade-Iranaq M.H.:
Tehran, Iran
Universal Scientific Education and Research Network (USERN), Tehran University of Medical Sciences, Tehran, Iran
Amu H.:
Department of Population and Behavioural Sciences, University of Health and Allied Sciences, Ho, Ghana
Anoushiravani A.:
Tehran, Iran
Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Antony C.M.:
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
Arabloo J.:
Tehran, Iran
Health Management and Economics Research Center, Shefa Neuroscience Research Center, Tehran, Iran
Aravkin A.Y.:
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
Department of Applied Mathematics, University of Washington, Seattle, WA, United States
School of Medicine, University of Washington, Seattle, WA, United States
Arkew M.:
Department of Medical Laboratory Sciences, Haramaya University, Harar, Ethiopia
Arndt M.B.:
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
Department of Global Health, University of Washington, Seattle, WA, United States
Arnlov J.:
Tehran, Iran
Department of Neurobiology, Care Sciences and Society, Shefa Neuroscience Research Center, Tehran, Iran
Aruleba R.T.:
East Carolina University, Greenville, NC, United States
Arumugam A.:
Department of Physiotherapy, Sharjah, United Arab Emirates
Asadi-Lari M.:
Tehran, Iran
Department of Epidemiology, Shefa Neuroscience Research Center, Tehran, Iran
Ayatollahi H.:
Tehran, Iran
Health Management and Economics Research Center, Shefa Neuroscience Research Center, Tehran, Iran
Department of Health Information Management, Shefa Neuroscience Research Center, Tehran, Iran
Ayyoubzadeh S.M.:
Tehran, Iran
Department of Health Information Management, Tehran University of Medical Sciences, Tehran, Iran
Azadnajafabad S.:
Tehran, Iran
Non-communicable Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran
Bagheri N.:
Research School of Population Health, Australian National University, Canberra, ACT, Australia
Bahmanziari N.:
Tehran, Iran
Translational Ophthalmology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Green Published, Green Accepted, hybrid, All Open Access; Hybrid Gold Open Access
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