Metabolic Syndrome Components in Patients with Pituitary Adenoma
Por:
Gonzalez-Almazan, JA, Cortes-Contreras, AP, Flores-Rabasa, R, Mendez-Garcia, LA, Escobedo, G, Olvera, JLN, Carrillo-Ruiz, JD
Publicada:
1 feb 2024
Ahead of Print:
1 dic 2023
Resumen:
Pituitary adenomas are benign tumors of the anterior portion of the pituitary gland (adenohypophysis), representing the 25% of all the tumor alterations. Pituitary adenomas are classified by the type of hormone secreted, cellularity, size, and structural alterations by the hormonal segregation. The diagnosis consists on the histopathological identification of cell types and the image-guided by magnetic resonance or tomography; the treatment can be both pharmacological and surgical. Metabolic Syndrome is the set of clinical conditions that increase the risk of cardiovascular diseases with an estimated prevalence of 25% worldwide. The alterations of metabolic syndrome are obesity, hypertension, dyslipidemia, insulin resistance, and diabetes mellitus type II. Pituitary adenomas and metabolic syndrome have an important relationship, hormone-secreting by pituitary adenomas affects a myriad of signaling pathways, which allows a favorable environment for the appearance of the metabolic syndrome. Moreover, patients with pituitary adenomas are shown to have an improvement in metabolic parameters after the medical/surgical treatment. The objective of this review is to explore the possible mechanisms through which PAs contributes to MetSx.
Filiaciones:
Gonzalez-Almazan, JA:
Gen Hosp Mexico, Res Div, Mexico City, Mexico
Gen Hosp, Funct & Stereotact Neurosurg Unit, Mexico City, Mexico
Univ Nacl Autonoma, Fac Estudios Super Iztacala, Mexico Fac Estudios Super Iztacala, Tlalnepantla, Mexico
Cortes-Contreras, AP:
Gen Hosp Mexico, Res Div, Mexico City, Mexico
Gen Hosp, Funct & Stereotact Neurosurg Unit, Mexico City, Mexico
Univ Nacl Autonoma Mexico, Fac Med, Dept Physiol, Mexico City 04510, Mexico
Flores-Rabasa, R:
Gen Hosp Mexico, Res Div, Mexico City, Mexico
Anahuac Univ Mex, Fac Hlth Sci, Southern Campus, Mexico City, Mexico
Mendez-Garcia, LA:
Gen Hosp Mexico, Res Div, Mexico City, Mexico
Escobedo, G:
Gen Hosp Mexico, Res Div, Mexico City, Mexico
Olvera, JLN:
Gen Hosp, Funct & Stereotact Neurosurg Unit, Mexico City, Mexico
Carrillo-Ruiz, JD:
Gen Hosp Mexico, Res Div, Mexico City, Mexico
Gen Hosp, Funct & Stereotact Neurosurg Unit, Mexico City, Mexico
Anahuac Univ, Psychol Fac, Coordinat Neurosci, Mexico City, Mexico
All Open Access; Bronze Open Access
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