Reliability assessment and validation of the postacne hyperpigmentation index (PAHPI), a new instrument to measure postinflammatory hyperpigmentation from acne vulgaris
Por:
Savory S.A., Agim N.G., Mao R., Peter S., Maldonado G., Bearden Dietert J., Lieu T.J., Wang C., Pretzlaff K., Das S., Vandergriff T., Lopez I.E., Litzner B.R., Hynan L.S., Arellano-Mendoza M.I., Bergstresser P.R., Pandya A.G.
Publicada:
1 ene 2014
Categoría:
Dermatology
Resumen:
Background There are no validated outcome measures for postinflammatory hyperpigmentation (PIH). Objective We sought to determine the reliability and validity of an outcome measure for PIH after acne in patients with skin of color. Methods A postacne hyperpigmentation index (PAHPI) was developed. Six raters scored 21 patients with PIH twice. Reliability was determined within and between raters, whereas validity was evaluated by comparing scores with severity ranking by an independent dermatologist. The pigment intensity scores were compared with the melanin index of each patient using a narrowband reflectance spectrophotometer. A quality-of-life score (Skindex-29) was also compared with PAHPI scores. Results Total PAHPI scores showed good reliability within and between raters and were valid when compared with clinical severity and melanin indices. Good correlation was achieved between the total PAHPI score and the emotion subscale of the Skindex-29. Limitations Generalizability of results is limited to African American females. Conclusion The PAHPI shows good reliability and validity when scored on patients with PIH from acne vulgaris. The PAHPI also correlates well with the emotional impact of PIH as measured by the Skindex-29. Future studies should assess the ability of the PAHPI to change with improvement of PIH from acne after treatment. © 2013 by the American Academy of Dermatology, Inc.
Filiaciones:
Savory S.A.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Agim N.G.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Mao R.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Peter S.:
Meharry Medical College, Nashville, TN, United States
Maldonado G.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Bearden Dietert J.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Lieu T.J.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Wang C.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Pretzlaff K.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Das S.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Vandergriff T.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Lopez I.E.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Litzner B.R.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Hynan L.S.:
Department of Clinical Sciences (Biostatistics) and Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, United States
Arellano-Mendoza M.I.:
Hospital General de Mexico, Mexico City, Mexico
Bergstresser P.R.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
Pandya A.G.:
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9190, United States
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