Recent advances in modified poly (lactic acid) as tissue engineering materials
Por:
Castaneda-Rodriguez, Samanta, Gonzalez-Torres, Maykel, Ribas-Aparicio, Rosa Maria, Del Prado-Audelo, Maria Luisa, Leyva-Gomez, Gerardo, Gurer, Eda Soenmez, Sharifi-Rad, Javad
Publicada:
20 mar 2023
Resumen:
As an emerging science, tissue engineering and regenerative medicine
focus on developing materials to replace, restore or improve organs or
tissues and enhancing the cellular capacity to proliferate, migrate and
differentiate into different cell types and specific tissues. Renewable
resources have been used to develop new materials, resulting in attempts
to produce various environmentally friendly biomaterials. Poly (lactic
acid) (PLA) is a biopolymer known to be biodegradable and it is produced
from the fermentation of carbohydrates. PLA can be combined with other
polymers to produce new biomaterials with suitable physicochemical
properties for tissue engineering applications. Here, the advances in
modified PLA as tissue engineering materials are discussed in light of
its drawbacks, such as biological inertness, low cell adhesion, and low
degradation rate, and the efforts conducted to address these challenges
toward the design of new enhanced alternative biomaterials.
Filiaciones:
Castaneda-Rodriguez, Samanta:
CONACYT, Mexico City, Mexico
Inst Nacl Rehabil, Lab Biotecnol, Mexico City, Mexico
Inst Politecn Nacl IPN, Escuela Nacl Ciencias Biol, Mexico City, Mexico
Gonzalez-Torres, Maykel:
CONACYT, Mexico City, Mexico
Inst Nacl Rehabil, Lab Biotecnol, Mexico City, Mexico
Inst Politecn Nacl IPN, Escuela Nacl Ciencias Biol, Mexico City, Mexico
Ribas-Aparicio, Rosa Maria:
Inst Politecn Nacl IPN, Escuela Nacl Ciencias Biol, Mexico City, Mexico
Del Prado-Audelo, Maria Luisa:
Tecnol Monterrey, Escuela Ingn & Ciencias, Campus Ciudad de Mexico, Mexico City, Mexico
Leyva-Gomez, Gerardo:
Univ Nacl Autonoma Mexico, Fac Quim, Dept Farm, Mexico City, Mexico
Gurer, Eda Soenmez:
Sivas Cumhuriyet Univ, Fac Pharm, Dept Pharmacognosy, Sivas, Turkiye
Sharifi-Rad, Javad:
Univ Azuay, Fac Med, Cuenca, Ecuador
Green Published, gold, All Open Access, Gold, Green
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