The honey bees immune memory
Por:
Burciaga R.A., Ruiz-Guzmán G., Lanz-Mendoza H., Krams I., Contreras-Garduño J.
Publicada:
1 ene 2023
Resumen:
Invertebrates' immune priming or innate immune memory is an analogous response to the vertebrates' adaptive memory. We investigated if honey bees have immune memory. We compared survival and immune response between bees that were: 1) manipulated (Naïve), 2) challenged twice with the same pathogen Escherichia coli (Memory), 3) challenged twice with different pathogens (Staphylococcus aureus versus E. coli, Micrococcus lysodeikticus versus E. coli), or 4) with PBS (the diluent of bacteria) versus E. coli (heterologous challenge; Control). Results indicate better survival in the Memory than the Control group, and the Memory group showed a similar survival than Naïve insects. The Memory group had higher lytic activity but lower prophenoloxidase, phenoloxidase activity, and hemocyte count than the Control and Naïve groups. No differences were found in relative expression of defensin-1. This first demonstration of immune memory opens the questions about its molecular mechanisms and whether, immune memory could be used against natural parasites that affect honey bees, hence, if they could be “vaccinated” against some natural parasites. © 2022 Elsevier Ltd
Filiaciones:
ENES, Unidad Morelia, UNAM. Antigua Carretera a Pátzcuaro, No.8701. Col. Ex-Hacienda San José de la Huerta Código, Michoacán, Morelia, 58190, Mexico
Instituto Nacional de Salud Pública, Morelos, Cuernavaca, Mexico
Institute of Ecology and Earth Sciences, University of Tartu, Tartu, Estonia
Department of Biotechnology, Daugavpils University, Daugavpils, Latvia
Department of Zoology and Animal Ecology, University of Latvia, Riga, Latvia
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