Mini-exon gene reveals circulation of TcI Trypanosoma cruzi (Chagas, 1909) (Kinetoplastida, Trypanosomatidae) in bats and small mammals in an ecological reserve in southeastern Mexico
Por:
Gomez-Sanchez, Eliza F., Ochoa-Diaz-Lopez, Hector, Espinoza-Medinilla, Eduardo E., Daniel Velazquez-Ramirez, D., Gabriela Santos-Hernandez, Nancy, Ruiz-Castillejos, Christian, Vidal-Lopez, Dolores G., Moreno-Rodriguez, Adriana, Laura Flores-Villegas, Any, Lopez-Argueta, Eduardo, De Fuentes-Vicente, Jose A.
Publicada:
28 ene 2022
Resumen:
A wide variety of mammals are involved in the sylvatic cycle of
Trypanosoma cruzi, the causative agent of Chagas disease. In many areas
in Latin America where T. cruzi is endemic, this cycle is poorly known,
and its main reservoirs have not been identified. In this study we
analyzed T. cruzi infection in bats and other small mammals from an
Ecological Reserve in southeastern Mexico. From January through March
2021, we captured wild individuals to extract cardiac and peripheral
blood, and infection was detected by PCR of the mini-exon gene. In bats,
the prevalence of infection was 16.36%, while in small mammals the
prevalence was 28.57%. All of the samples that were positive for T.
cruzi were identified as the TCI genotype. Our findings suggest that
this zone, situated at the periphery of urban zones might have
epidemiological relevance in the sylvatic cycle of T. cruzi and needs to
be monitored. The infection of bats in this area is particularly
concerning since the flight pattern of this populations overlaps with
human settlements. Despite being subject to conservation protections,
there continue to be anthropogenic actions that disturb the study area,
which could exacerbate risks to public health.
Filiaciones:
Gomez-Sanchez, Eliza F.:
Univ Ciencias & Artes Chiapas, Lab Invest & Diagnost Mol, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
Ochoa-Diaz-Lopez, Hector:
Colegio Frontera Sur, Dept Salud, Tuxtla Gutierrez, Chiapas, Mexico
Espinoza-Medinilla, Eduardo E.:
Univ Ciencias & Artes Chiapas, Lab Invest & Diagnost Mol, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
Daniel Velazquez-Ramirez, D.:
Colegio Frontera Sur, Dept Salud, Tuxtla Gutierrez, Chiapas, Mexico
Gabriela Santos-Hernandez, Nancy:
Univ Ciencias & Artes Chiapas, Lab Invest & Diagnost Mol, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
Ruiz-Castillejos, Christian:
Univ Ciencias & Artes Chiapas, Lab Invest & Diagnost Mol, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
Vidal-Lopez, Dolores G.:
Univ Ciencias & Artes Chiapas, Lab Multidisciplinario Expt & Bioterio, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
Moreno-Rodriguez, Adriana:
Univ Autonoma Benito Judrez Oaxaca, Lab 16, Fac Ciencias Quim, Oaxaca, Oaxaca, Mexico
Laura Flores-Villegas, Any:
Univ Nacl Autonoma Mexico, Lab Biol Panisitos, Fac Med, Mexico City, DF, Mexico
Lopez-Argueta, Eduardo:
Univ Ciencias & Artes Chiapas, Lab Invest & Diagnost Mol, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
De Fuentes-Vicente, Jose A.:
Univ Ciencias & Artes Chiapas, Lab Invest & Diagnost Mol, Inst Ciencias Biol, Tuxtla Gutierrez, Mexico
gold, Green Published
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