Dependence of Heart Rate Variability Indices on the Mean Heart Rate in Women with Well-Controlled Type 2 Diabetes
Por:
Robles-Cabrera, Adriana, Torres-Arellano, Jose M., Fossion, Ruben, Lerma, Claudia
Publicada:
1 oct 2021
Categoría:
Medicine (miscellaneous)
Resumen:
Heart rate variability (HRV) is a method used to evaluate the presence
of cardiac autonomic neuropathy (CAN) because it is usually attributed
to oscillations in cardiac autonomic nerve activity. Recent studies in
other pathologies suggest that HRV indices are strongly related to mean
heart rate, and this does not depend on autonomic activity only. This
study aimed to evaluate the correlation between the mean heart rate and
the HRV indices in women patients with well-controlled T2DM and a
control group. HRV was evaluated in 19 T2DM women and 44 healthy women
during basal supine position and two maneuvers: active standing and
rhythmic breathing. Time-domain (SDNN, RMSSD, pNN20) and
frequency-domain (LF, HF, LF/HF) indices were obtained. Our results show
that meanNN, age, and the maneuvers are the main predictors of most HRV
indices, while the diabetic condition was a predictor only for pNN20.
Given the known reduced HRV in patients with T2DM, it is clinically
important that much of the HRV indices are dependent on heart rate
irrespective of the presence of T2DM. Moreover, the multiple regression
analyses evidenced the multifactorial etiology of HRV.
Filiaciones:
Biomedical Sciences, National Autonomous University of Mexico, Mexico City, 04510, Mexico
Department of Electromechanical Instrumentation, National Institute of Cardiology Ignacio Chávez, Mexico City, 14080, Mexico
Center for Complexity Sciences (C3), National Autonomous University of Mexico, Mexico City, 04510, Mexico
Institute for Nuclear Science, National Autonomous University of Mexico, Mexico City, 04510, Mexico
Green Published, gold, All Open Access; Gold
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