Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions
Por:
Méndez-Sánchez N., Zamarripa-Dorsey F., Panduro A., Purón-González E., Coronado-Alejandro E.U., Cortez-Hernández C.A., de la Tijera F.H., Pérez-Hernández J.L., Cerda-Reyes E., Rodríguez-Hernández H., Cruz-Ramón V.C., Ramírez-Pérez O.L., Aguilar-Olivos N.E., Rodríguez-Martínez O.F., Cabrera-Palma S., Cabrera-álvarez G.
Publicada:
1 ene 2018
Resumen:
AIM To investigate the main current etiologies of cirrhosis in Mexico. METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period (January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years (SD = 12.1), and the percentages of men and women were similar (52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus (HCV) (36.2%), alcoholic liver disease (ALD) (31.2%), and nonalcoholic steatohepatitis (23.2%), and the least frequent were hepatitis B virus (1.1%), autoimmune disorders (7.3%), and other conditions (1.0%). CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease (NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. © The Author(s) 2018.
Filiaciones:
Liver Research Unit, Medica Sur Clinic and Foundation, Mexico City, 14050, Mexico
Department of Gastroenterology, Hospital 'Juárez' of México, Mexico City, 07760, Mexico
Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara 'Fray Antonio Alcalde', Guadalajara, Jalisco, 44280, Mexico
Department of Internal Medicine, 'Christus Muguerza 'Super Specialty' Hospital' Monterrey, Monterrey, Nuevo León, 64060, Mexico
Department of Gastroenterology, 'University Hospital 'Jose Eleuterio González' Monterrey, Monterrey, Nuevo León, 64060, Mexico
Department of Gastroenterology, 'General Hospital of Mexico 'Dr. Eduardo Liceaga', Mexico City, 06720, Mexico
Department of Gastroenterology, 'Central Military Hospital', Mexico City, 11200, Mexico
Faculty of Medicine and Nutrition, Juárez University of the State of Durango, Durango, 34100, Mexico
Liver Clinic, Regional General Hospital IMSS 1, Cuernavaca, Morelos, 62450, Mexico
All Open Access, Gold
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