RegulomePA: a database of transcriptional regulatory interactions in Pseudomonas aeruginosa PAO1
Por:
Galan-Vasquez, Edgardo, Carely Luna-Olivera, Beatriz, Ramirez-Ibanez, Marcelino, Martinez-Antonio, Agustino
Publicada:
1 dic 2020
Resumen:
We present RegulomePA, a database that contains biological information
on regulatory interactions between transcription factors (TFs), sigma
factor (SFs) and target genes in Pseudomonas aeruginosa PAO1. RegulomePA
consists of 4827 regulatory interactions between 2831 nodes, which
represent the interactions of TFs and SFs with their target genes, from
the total of predicted RegulomePA including 27.27% of the TFs, 54.16%
of SFs and 50.8% of the total genes. Each entry in the database
corresponds to one node in the network and provides comprehensive
details about the gene and its regulatory interactions such as gene
description, nucleotide sequence, genome-strand position and links to
other databases as well as the type of regulation it exerts or to which
it is being subject (repression or activation), the associated
experimental evidence and references, and topological information.
Additionally, RegulomePA provides a way to recover information on the
regulatory circuits of the network to which a gene pertains and also
makes available the source codes to analyze the topology of any other
regulatory network. The database will be updated yearly, by our team,
with the contributions from ourselves and users, since the users are
provided with an interactive platform where they can add interactions to
the regulatory network feeding it with their respective references.
Filiaciones:
Galan-Vasquez, Edgardo:
Univ Nacl Autonoma Mexico, Inst Invest Matemat Aplicadas & Sistemas, Dept Ingn Sistemas Comp & Automatizac, Circuito Escolar 3000,Ciudad Univ, Ciudad De Mexico 04510, Mexico
Carely Luna-Olivera, Beatriz:
UPN Unidad 201, Acad Matemat, Camino Zanjita, Oaxaca De Juarez 71230, Oaxaca, Mexico
Ctr Altos Estudios Mixteca, CALMIX, Oaxaca, Oaxaca, Mexico
Ramirez-Ibanez, Marcelino:
UPN Unidad 201, Acad Matemat, Camino Zanjita, Oaxaca De Juarez 71230, Oaxaca, Mexico
Ctr Altos Estudios Mixteca, CALMIX, Oaxaca, Oaxaca, Mexico
CONACyT UPN Unidad 201, Camino Zanjita, Oaxaca De Juarez 71230, Oaxaca, Mexico
Martinez-Antonio, Agustino:
Natl Polytech Inst, Irapuato Unit, Ctr Res & Adv Studies, Genet Engn Dept, Km 9-6 Libramiento Norte Carretera Irapuato Leon, Irapuato Guanajuato 36824, Mexico
Green Published, gold
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