Porogen Effect on Structural and Physical Properties of ß-TCP Scaffolds for Bone Tissue Regeneration
Por:
Ruiz-Aguilar, C., Olivares-Pinto, U., Drew R.A.L., Aguilar-Reyes, E. A., Alfonso, I
Publicada:
1 oct 2021
Ahead of Print:
1 ene 2020
Resumen:
Scaffolds for bone tissue applications have been an outstanding alternative to repair and regenerate bone tissue defects caused by traumas or illness. There are many methods available to fabricate porous scaffold such as solvent casting, gas bubble, phase separation, electrospinning, particle-leaching, among others. The particle-leaching technique has shown advantages in bone tissue regeneration applications, the main benefit of this technique is related to the porogen particle size and the porogen content in the manufacture of scaffolds. Tricalcium phosphate is one calcium phosphate that presented appropriated characteristic to be used for bone tissue engineering due to the chemical properties similar to the human bones. Scaffolds of tricalcium phosphate ß phase were made using sugar particles. The porogen was varied in amounts of 50, 60 and 70 wt.% of two commercial sugars with the remainder of the composition made up of tricalcium phosphate powders. The pore sizes in all the scaffolds were in the range of 90 to 600 µm with an irregular pore morphology and the porosity was in the range of 63 to 77%. © 2020 AGBM
Filiaciones:
Ruiz-Aguilar, C.:
Escuela Nacional de Estudios Superiores Unidad Juriquilla, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, Boulevard Juriquilla 3001, Santiago de Querétaro, Qro. CP 76230, Mexico
Olivares-Pinto, U.:
Escuela Nacional de Estudios Superiores Unidad Juriquilla, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, Boulevard Juriquilla 3001, Santiago de Querétaro, Qro. CP 76230, Mexico
Drew R.A.L.:
Department of Mechanical, Industrial and Aerospace Engineering, Concordia University, 1455 Maisonneuve Blvd West, Montreal, QC H3G 1M8, Canada
Aguilar-Reyes, E. A.:
Instituto de Investigación en Metalurgia y Materiales, Universidad Michoacana de San Nicolás de Hidalgo, Av. Francisco J. Múgica S/N, Morelia, Mich. CP 58030, Mexico
Alfonso, I:
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Unidad Morelia, Antigua Carretera a Pátzcuaro 8701, Ex-Hacienda San José de la Huerta, Morelia, Mich. CP 58190, Mexico
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