Unexpected cytotoxicity of TiO2-coated magnesium alloys
Por:
Morquecho-Marin, Daniela, Silva-Bermudez, Phaedra, Millan-Ramos, Benjamin, Victoria-Hernandez, Jose, Letzig, Dietmar, Ramirez-Ortega, David, Depablos-Rivera, Osmary, Garcia-Lopez, Julieta, Barrera-Ortega, Cecilia C., Rodil, Sandra E.
Publicada:
1 oct 2020
Resumen:
Biodegradable Mg-based alloys have attracted increasing attention from
orthopedic surgeons and biomaterials scientists since their Young's
modulus is close to that of bone. However, control of the degradation
rate is still a challenge. Sputtered TiO2 coatings were deposited on
Mg-Zn-Ca alloys aiming to reduce the initial strong reactivity of Mg
with biological fluids. However, the degradation tests indicated that
the coated samples induced a larger variation in the pH, greater H-2
production and formation of degradation products in comparison to the
bare alloys. Consequently, an enhanced cytotoxicity of the coated
samples was observed. (C) 2020 Elsevier B.V. All rights reserved.
Filiaciones:
Morquecho-Marin, Daniela:
Inst Nacl Rehabil Luis Guillermo Ibarra Ibarra, Unidad Ingn Tejidos Terapia Celular & Med Regener, Cdmx 14389, Mexico
Univ Nacl Autonoma Mexico, Posgrad Ciencias Med Odontol & Salud, Cdmx 14389, Mexico
Silva-Bermudez, Phaedra:
Inst Nacl Rehabil Luis Guillermo Ibarra Ibarra, Unidad Ingn Tejidos Terapia Celular & Med Regener, Cdmx 14389, Mexico
Millan-Ramos, Benjamin:
Univ Nacl Autonoma Mexico, Inst Invest Mat, Cdmx 04510, Mexico
Univ Nacl Autonoma Mexico, Posgrad Ciencia & Ingn Mat, Cdmx 04510, Mexico
Victoria-Hernandez, Jose:
Helmholtz Zentrum Geesthacht, Magnesium Innovat Ctr Mag, Inst Mat Res, D-21502 Geesthacht, Germany
Letzig, Dietmar:
Helmholtz Zentrum Geesthacht, Magnesium Innovat Ctr Mag, Inst Mat Res, D-21502 Geesthacht, Germany
Ramirez-Ortega, David:
Univ Nacl Autonoma Mexico, Inst Invest Mat, Cdmx 04510, Mexico
Depablos-Rivera, Osmary:
Univ Nacl Autonoma Mexico, Inst Invest Mat, Cdmx 04510, Mexico
Garcia-Lopez, Julieta:
Inst Nacl Rehabil Luis Guillermo Ibarra Ibarra, Unidad Ingn Tejidos Terapia Celular & Med Regener, Cdmx 14389, Mexico
Barrera-Ortega, Cecilia C.:
Univ Nacl Autonoma Mexico, Fac Estudios Super Iztacala, D-54090 Edo De Mexico, Germany
Rodil, Sandra E.:
Univ Nacl Autonoma Mexico, Inst Invest Mat, Cdmx 04510, Mexico
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