Coinfection byTrypanosoma cruziand a fungal pathogen increases survival of Chagasic bugs: advice against a fungal control strategy
Por:
Laura Flores-Villegas, A., Cabrera-Bravo, Margarita, De Fuentes-Vicente, Jose A., Guillermo Jimenez-Cortes, J., Salazar-Schettino, Paz Maria, Bucio-Torres, Martha Irene, Cordoba-Aguilar, Alex
Publicada:
1 jun 2020
Resumen:
Triatomine bugs carry the parasitic protozoaTrypanosoma cruzi, the
causal agent of Chagas disease. It is known that both the parasite and
entomopathogenic fungi can decrease bug survival, but the combined
effect of both pathogens is not known, which is relevant for biological
control purposes. Herein, the survival of the triatomineMeccus
pallidipennis(Stal, 1872) was compared when it was coinfected with the
fungusMetarhizium anisopliae(Metschnikoff) andT. cruzi, and when both
pathogens acted separately. The immune response of the insect was also
studied, using phenoloxidase activity in the bug gut and hemolymph, to
understand our survival results. Contrary to expectations, triatomine
survival was higher in multiple than in single challenges, even though
the immune response was lower in cases of multiple infection. We
postulate thatT. cruziexerts a protective effect and/or that the insect
reduced the resources allocated to defend itself against both pathogens.
Based on the present results, the use ofM. anisopliaeas a control agent
should be re-considered.
Filiaciones:
Laura Flores-Villegas, A.:
Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Mexico City, DF, Mexico
Cabrera-Bravo, Margarita:
Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Mexico City, DF, Mexico
De Fuentes-Vicente, Jose A.:
Univ Ciencias & Artes Chiapas, Inst Ciencias Biol, Libramiento Norte Poniente 1150, Tuxtla Gutierrez 29029, Chiapas, Mexico
Guillermo Jimenez-Cortes, J.:
Univ Nacl Autonoma Mexico, Inst Ecol, Dept Ecol & Evolut, Apdo P 70-275,Ciudad Univ, Mexico City 04510, DF, Mexico
Salazar-Schettino, Paz Maria:
Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Mexico City, DF, Mexico
Bucio-Torres, Martha Irene:
Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Mexico City, DF, Mexico
Cordoba-Aguilar, Alex:
Univ Nacl Autonoma Mexico, Inst Ecol, Dept Ecol & Evolut, Apdo P 70-275,Ciudad Univ, Mexico City 04510, DF, Mexico
|