Characterization of mechanically reinforced electrospun dextrin-polyethylene oxide sub-microfiber mats
Por:
Rodriguez-Zamora, Penelope, Peña-Juárez M.C., Cedillo-Servin, Gerardo, Paloalto-Landon, Alejandro, Ortega-Garcia, Ivan, Maaza, Malik, Vera-Graziano, Ricardo
Publicada:
1 ene 2019
Resumen:
Dextrin and dextrin-polyethylene oxide (DEX/PEO) fibers in the submicron range were produced by electrospinning of single and blend polymer solutions. The morphology, intermolecular interactions, and mechanical properties of dextrin microfibers with and without PEO were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, X-ray diffraction, nuclear magnetic resonance spectroscopy, and uniaxial tensile testing. Spectroscopic results confirmed hydrogen bond formation, evidencing dextrin as a molecular entanglement source for fiber mechanical reinforcement. The uniaxial tensile tests demonstrated a synergistic mechanical reinforcement effect that varied with blend composition. Equal weight ratio blends supported a maximum tensile strength with a high elastic modulus and demonstrated to be more elastic and resistant to breaking, even than pristine PEO fibers. Moreover, elastic moduli of blend fiber mats were found to lie within the value range for human skin, thus providing the DEX/PEO meshes with potential applicability as skin tissue scaffolds. This synthesis approach proved the feasible and inexpensive fabrication process of natural-synthetic polymer hybrid fibers that combine the biocompatibility, biodegradability, and encapsulating capability of dextrin with the mechanical strength and flexibility of PEO for the development of scaffolds for tissue engineering and topical drug delivery applications in skin wound healing. POLYM. ENG. SCI., 59:1778–1786, 2019. © 2019 Society of Plastics Engineers. © 2019 Society of Plastics Engineers
Filiaciones:
Rodriguez-Zamora, Penelope:
Instituto de Física, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Univ Nacl Autonoma Mexico, Inst Fis, Mexico City 04510, DF, Mexico
Peña-Juárez M.C.:
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Cedillo-Servin, Gerardo:
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Univ Nacl Autonoma Mexico, Inst Invest Mat, Mexico City 04510, DF, Mexico
Paloalto-Landon, Alejandro:
Instituto de Física, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Univ Nacl Autonoma Mexico, Inst Fis, Mexico City 04510, DF, Mexico
Ortega-Garcia, Ivan:
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Univ Nacl Autonoma Mexico, Inst Invest Mat, Mexico City 04510, DF, Mexico
Maaza, Malik:
UNESCO Africa Chair in Nanosciences & Nanotechnology, College of Graduate Studies, University of South Africa, Muckleneuk Ridge, P.O. Box 392, Pretoria, South Africa
Nanosciences African Network (NANOAFNET), iThemba LABS-National Research Foundation, 1 Old Faure Road, Somerset West 7129, P.O. Box 722, Somerset West, Western Cape Province, South Africa
Univ South Africa, Coll Grad Studies, UNESCO Africa Chair Nanosci & Nanotechnol, POB 392, Pretoria, South Africa
Natl Res Fdn, IThemba LABS, Nanosci African Network NANOAFNET, 1 Old Faure Rd,POB 722, ZA-7129 Somerset West, Western Cape Pr, South Africa
Vera-Graziano, Ricardo:
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Univ Nacl Autonoma Mexico, Inst Invest Mat, Mexico City 04510, DF, Mexico
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