A life-course approach to early-onset of diabetes mellitus: Probable contribution of collective violence in Mexico
Por:
Hernandez-Montoya, Dewi, Soriano-Flores, Antonio, Castro-Santana, Anaclara, Benjet, Corina, Bernal-Perez, Pilar, Llanes-Diaz, Nathaly
Publicada:
1 jun 2019
Categoría:
Life-span and life-course studies
Resumen:
Type 2 diabetes mellitus (T2DM) is a growing health problem among the
pediatric population in the world, and particularly in Mexico. Official
data in Mexico reported that during the period from 2003 to 2013 there
was an increase in the cumulative incidence among older adolescents
between 2010 and 2012, which decreased to the usual measures in 2013.
All these variations occurred in a period in which collective violence
permeated all levels of Mexican society. It can be argued that there
might be a relationship between the two phenomena.
This is an ecologic analytical study of trends over time comprising
older adolescents (15-19 year olds). T2DM cumulative incidence and
mortality rates attributable to violent death (VD) were standardized by
direct method according to the World Health Organization. Data were
sourced from nationwide official reports. Time series analysis was
performed with ARIMA models and significant predictors. The disease
ecology analysis was done using cluster analysis.
Using significant predictors with ARIMA models, we found that the male
VD mortality rates series could forecast 63.1% of the temporal
variability of the cumulative incidence of T2DM series. Geographically,
states with higher rates of violence also showed a higher incidence of
T2DM.
These data suggest that collective violence may make some contribution
to the early onset of T2DM among adolescents, particularly in those
regions most affected by violence. These findings can be conducive to
opening new lines of research to explore the relationship between
variables at the individual level and the clinical implications.
Filiaciones:
Hernandez-Montoya, Dewi:
Inst Nacl Pediat, Insurgentes Sur 3700C, Mexico City 04530, DF, Mexico
Soriano-Flores, Antonio:
Univ Nacl Autonoma Mexico, Circuito Exterior S-N, Mexico City 04510, DF, Mexico
Castro-Santana, Anaclara:
Univ Nacl Autonoma Mexico, Circuito Exterior S-N, Mexico City 04510, DF, Mexico
Benjet, Corina:
Inst Nacl Psiquiatria, Calzada Mexico Xochimilco 101 Col San Lorenzo Hui, Mexico City 14370, DF, Mexico
Bernal-Perez, Pilar:
Inst Nacl Pediat, Insurgentes Sur 3700C, Mexico City 04530, DF, Mexico
Llanes-Diaz, Nathaly:
Consejo Nacl Ciencia & Technol, Inst Nacl Pediat, Insurgentes Sur 3700C, Mexico City 04530, DF, Mexico
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