Optical methods and image processing as a quantitative tool in photodynamic therapy: a proof of concept.
Por:
Rivera-Fernandez, Josue D., Roa-Tort, Karen, de la Rosa-Vazquez, Jose M., Valor-Reed, Alma, Stolik-Isakina, Suren, Fabila-Bustos, Diego A., Guzman-Arriaga, Carolina, Escobedo, Galileo
Publicada:
1 ene 2019
Resumen:
This paper presents the first results of the combination of optical
techniques, through fluorescence images captured by endoscopic
techniques, and imaging processing methods to give a quantitative result
that will be useful to physicians to observing and following up
Photodynamic Therapy (PDT) for liver cancer. The experiment was applied
to an animal model using delta-aminolevulinic acid (ALA) as a
photosensitizing agent, red light for the application of PDT, white
light for diffuse reflectance and light of 405 nm for the capture of
fluorescence photographs with endoscopic procedures on the surface of
the liver. As part of the image processing, metrics such as the
Euclidean distance were used and the RGB color composition components.
Filiaciones:
Rivera-Fernandez, Josue D.:
Inst Politecn Nacl ESIME Zacatenco, Lab Biofotonica, Mexico City 07738, DF, Mexico
Roa-Tort, Karen:
Inst Politecn Nacl ESIME Zacatenco, Lab Biofotonica, Mexico City 07738, DF, Mexico
de la Rosa-Vazquez, Jose M.:
Inst Politecn Nacl ESIME Zacatenco, Lab Biofotonica, Mexico City 07738, DF, Mexico
Valor-Reed, Alma:
Inst Politecn Nacl ESIME Zacatenco, Lab Biofotonica, Mexico City 07738, DF, Mexico
Stolik-Isakina, Suren:
Inst Politecn Nacl ESIME Zacatenco, Lab Biofotonica, Mexico City 07738, DF, Mexico
Fabila-Bustos, Diego A.:
Inst Politecn Nacl ESIME Zacatenco, Lab Biofotonica, Mexico City 07738, DF, Mexico
Inst Politecn Nacl, UPIIH, Lab Espectroscopia, San Agustin Tlaxiaca, Hidalgo, Mexico
Guzman-Arriaga, Carolina:
Univ Nacl Autonoma Mexico, Hosp Gen Mexico Dr Eduardo Liceaga, Fac Med, Unidad Med Expt, Mexico City 06726, DF, Mexico
Escobedo, Galileo:
Univ Nacl Autonoma Mexico, Hosp Gen Mexico Dr Eduardo Liceaga, Fac Med, Unidad Med Expt, Mexico City 06726, DF, Mexico
Univ Nacl Autonoma Mexico, Inst Invest Biomed, Dept Inmunol, Mexico City 04510, DF, Mexico
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