The other side of the superoxide radical anion: its ability to chemically repair DNA oxidized sites
Por:
Munoz-Rugeles, Leonardo, Galano, Annia, Raul Alvarez-Idaboy, Juan
Publicada:
18 dic 2018
Resumen:
The superoxide radical anion can repair oxidative damage. In particular,
it was demonstrated that O-2(-) can repair oxidized DNA by electron
transfer, restoring the original structure of this important molecule.
Acid-base equilibria have been considered, and the influence of the pH
on the main reaction mechanism has been explored.
Filiaciones:
Munoz-Rugeles, Leonardo:
Univ Nacl Autonoma Mexico, Fac Quim, Dept Fis & Quim Teor, Mexico City 04510, DF, Mexico
Galano, Annia:
Univ Autonoma Metropolitana Iztapalapa, Dept Quim, San Rafael Atlixco 186, Mexico City 09340, DF, Mexico
Raul Alvarez-Idaboy, Juan:
Univ Nacl Autonoma Mexico, Fac Quim, Dept Fis & Quim Teor, Mexico City 04510, DF, Mexico
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