Number of different binary functions generated by NK -Kauffman networks and the emergence of genetic robustness


Por: Romero D., Zertuche F.

Publicada: 1 ene 2007
Resumen:
We determine the average number (N,K) of NK -Kauffman networks that give rise to the same binary function. We show that for N1, there exists a connectivity critical value Kc such that (N,K) ? eN (>0) for K< Kc and (N,K) ?1 for K> Kc. We find that Kc is not a constant but scales very slowly with N as Kc ? log2 log2 (2Nln 2). The problem of genetic robustness emerges as a statistical property of the ensemble of NK -Kauffman networks and impose tight constraints in the average number of epistatic interactions that the genotype-phenotype map can have. © 2007 American Institute of Physics.

Filiaciones:
Romero D.:
 Instituto de Matemáticas, Universidad Nacional Autónoma de ?xico, Unidad Cuernavaca, A.P. 273-3, Cuernavaca, Morebs 62251, Mexico

Zertuche F.:
 Instituto de Matemáticas, Universidad Nacional Autónoma de ?xico, Unidad Cuernavaca, A.P. 273-3, Cuernavaca, Morebs 62251, Mexico
ISSN: 00222488
Editorial
AMER INST PHYSICS, CIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USA, Estados Unidos America
Tipo de documento: Article
Volumen: 48 Número: 8
Páginas:
WOS Id: 000249156400031
imagen All Open Access; Green

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