Vaccination against cysticercosis and hydatid disease
Por:
Lightowlers M.W., Flisser A., Gauci C.G., Heath D.D., Jensen O., Rolfe R.
Publicada:
1 ene 2000
Resumen:
Infections with the larval stages of taeniid cestode parasites cause substantial human morbidity as well as economic losses in domestic livestock species. Despite ongoing efforts around the world, few countries have been able substantially to reduce or eradicate these infections through the use of anthelmintics and lifestyle changes. Vaccines offer an additional potential tool to assist with the control of parasite transmission. Here, Marshall Lightowlers and colleagues review the substantial progress that has been made towards developing practical vaccines against hydatid disease in sheep and cysticercosis in sheep and cattle. Recombinant antigens have been used to induce more than 90% protection against challenge infections. Such success in animals encourages investigation of the potential use of vaccines in humans to prevent hydatid disease arising from infection with Echinococcus granulosus and cysticercosis from infection with Taenia solium. Copyright (C) 2000 Elsevier Science Ltd.
Filiaciones:
Lightowlers M.W.:
Marshall Lightowlers, Charles Gauci and Rick Rolfe are at The University of Melbourne, 250 Princes Highway, Werribee, VIC 3030, Australia
Flisser A.:
Institute Nacional de Diagnóstico y Referencia Epidemiológicos, SSa Carpio 470 DF, 11340 México DF and the Facultad de Medicina, Universidad Nacional Autonomica de México 04510 Mexico DF, Mexico
Gauci C.G.:
Marshall Lightowlers, Charles Gauci and Rick Rolfe are at The University of Melbourne, 250 Princes Highway, Werribee, VIC 3030, Australia
Heath D.D.:
AgResearch, Wallaceville Animal Research Centre, PO Box 40063, Upper Hutt, New Zealand
Jensen O.:
Programa de Control de la Hydatidosis, Chacra N18, 9020 Sarmiento, Chubut, Argentina
Rolfe R.:
Marshall Lightowlers, Charles Gauci and Rick Rolfe are at The University of Melbourne, 250 Princes Highway, Werribee, VIC 3030, Australia
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