Host cells in the spiral canal of taenia solium (Cestoda) Cysticerci
Por:
De La Torre P., Merchant M.T., Willms K., Laclette J.P.
Publicada:
1 ene 1998
Resumen:
The presence of host inflammatory cells inside the spiral canal of all viable Taenia solium cysts obtained from naturally infected pigs is described. Cells can penetrate into vicinity of suckers and rostellum, although most appear damaged, suggesting that conditions in the canal are deleterious for them. These observations extend the localization of the host inflammatory infiltrate to this intricate microniche, which may offer new approaches for the treatment of cysticercosis, based on a scolex-targeted action. The presence of host cells in the canal of cysts also poses the problem of the resulting contamination with host materials in the studies using cysts extracts. As an example, host DNA contamination is readily detectable in genomic DNA isolated from T. solium and Taenia taeniaeformis cysts, as demonstrated by polymerase chain rection amplification and subsequent sequencing of a segment of the 18S ribosomal gene.
Filiaciones:
De La Torre P.:
Department of Immunology, Inst. de Invest. Biomédicas, Univ. Nac. Auton. de México, A.P. 70228, México 04510 D.F., Mexico
Merchant M.T.:
Dept. of Microbiol. and Parasitology, Facultad de Medicina, UNAM, A.P. 70228, México 04510 D.F., Mexico
Willms K.:
Dept. of Microbiol. and Parasitology, Facultad de Medicina, UNAM, A.P. 70228, México 04510 D.F., Mexico
Laclette J.P.:
Department of Immunology, Inst. de Invest. Biomédicas, Univ. Nac. Auton. de México, A.P. 70228, México 04510 D.F., Mexico
|