Post-trial injection of atropine into the caudate nucleus interferes with long-term but not with short-term retention of passive avoidance
Por:
Prado-Alcalá R.A., Signoret-Edward L., Figueroa M., Giordano M., Barrientos M.A.
Publicada:
1 ene 1984
Resumen:
One-trial passive avoidance training was given to Wistar rats and retention of the task was measured 30 min and 24 h later. Atropine (60 ?g) was injected into the anterior caudate nucleus 2 min after training. Excellent retention was evident 30 min after training, whereas a significant deficit in memory was found when retention was tested 24 h after training. These results suggest that blockade of cholinergic activity of the caudate nucleus induced shortly after training interferes with the consolidation of long-term memory but not with short-term memory processes. © 1984 Academic Press, Inc.
Filiaciones:
Psychophysiology Laboratory, School of Psychology, Anahuac University, and Department of Physiology, Faculty of Medicine, National University of México, México, D.F. 04510, México
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