Stability of unstimulated and stimulated whole saliva flow rates in children
Por:
Sanchez-Perez, Leonor, Irigoyen-Camacho, Esther, Saenz-Martinez, Laura, Zepeda Zepeda, Marco, Acosta-Gio, Enrique, Mendez-Ramirez, Ignacio
Publicada:
1 sep 2016
Categoría:
Dentistry (miscellaneous)
Resumen:
Objective. To analyze the stability of the unstimulated saliva flow rate
(USFR) and the stimulated saliva flow rate (SSFR) in children followed
from age 7 to 12 years old.
Methods. Longitudinal study. Whole saliva samples were collected from
school children (50 girls and 50 boys). Forty-four girls and 32 boys
remained in this cohort for 6 years (dropout rate 24%). Variables that
could influence USFR or SSFR patterns were analyzed in a
repeated-measures MANOVA.
Results. Over a 6-year follow-up, the children's USFR ranged from 0.41
to 0.46 mL/min in the initial and final observation, respectively, and
showed no significant differences (P = 0.4455) during the follow-up. The
children consistently belonged to one of three distinct SSFR groups (P <
0.0001). A repeated-measures MANOVA model showed that USFR and SSFR were
not associated with sex, body mass index, or indoor temperature during
sampling.
Conclusion. These results indicate that USFR and SSFR patterns were
stable from 7 to 12 years old. This finding may be useful in oral health
prevention or treatment and in the search for biomarkers in saliva for
screening or diagnostic purposes.
Filiaciones:
Sanchez-Perez, Leonor:
Metropolitan Autonomous Univ, Xochimilco Unit, Hlth Care Dept, Area Res Clin Sci, Mexico City, DF, Mexico
Irigoyen-Camacho, Esther:
Metropolitan Autonomous Univ, Xochimilco Unit, Hlth Care Dept, Area Res Clin Sci, Mexico City, DF, Mexico
Saenz-Martinez, Laura:
Metropolitan Autonomous Univ, Xochimilco Unit, Hlth Care Dept, Area Res Clin Sci, Mexico City, DF, Mexico
Zepeda Zepeda, Marco:
Metropolitan Autonomous Univ, Xochimilco Unit, Hlth Care Dept, Area Res Clin Sci, Mexico City, DF, Mexico
Acosta-Gio, Enrique:
Univ Nacl Autonoma Mexico, Sch Dent, Microbiol Lab, Mexico City, DF, Mexico
Mendez-Ramirez, Ignacio:
Univ Nacl Autonoma Mexico, Inst Res Appl Math & Syst, Mexico City, DF, Mexico
|