Follow up of natural infection with Trypanosoma cruzi in two mammals species, Nasua narica and Procyon lotor (Carnivora: Procyonidae): Evidence of infection control?
Por:
Martínez-Hernández F., Rendon-Franco E., Gama-Campillo L.M., Villanueva-García C., Romero-Valdovinos M., Maravilla P., Alejandre-Aguilar R., Rivas N., Córdoba-Aguilar A., Munoz-Garcia, CI, Villalobos G.
Publicada:
29 ago 2014
Resumen:
Background: A large variety of mammals act as natural reservoirs of Trypanosoma cruzi (the causal agent of Chagas disease) across the American continent. Related issues are infection and parasite burden in these reservoirs, and whether they are able to control T. cruzi infections. These parameters can indicate the real role of mammals as T. cruzi reservoirs and transmitters. Here, two species of mammals, white-nosed coati (Nasua narica) and raccoon (Procyon lotor), were examined for to determine: a) T. cruzi presence, and; b) their ability to control T. cruzi infection. Methods: Multiple capture-recaptures of both species were carried out in semi-wild conditions in Villahermosa, Tabasco, Mexico, for 5 years. Two samplings per year (summer and winter) took place. Prevalence and pattern of T. cruzi infection were determined by PCR from both mammals' blood samples. Results: Raccoon samples had a higher relative infection values (26.6%) compared to those of white-nosed coati (9.05%), being this difference significant in summer 2012 (P < 0.00001), summer (P = 0.03) and winter 2013 (P = 0.02). Capture and recapture data indicated three infection dynamics: 1) negative-positive-negative infection; 2) positive-negative-positive infection; and 3) positive at all sampling times. Conclusions: These results indicate that both coati and raccoons may be able to control T. cruzi infection. Thus, the role as efficient reservoirs could be questioned (at least for those times when mammals are able to tolerate the infection). However, while infected, they may also be able to approach human dwellings and play a role important in linking sylvatic and domestic cycles. © 2014 Martínez-Hernández et al.;.
Filiaciones:
Univ Nacl Autonoma Mexico, Inst Ecol, Dept Ecol Evolut, Mexico City 04510, DF, Mexico
Departamento de Ecología de Agentes Patógenos, Hospital General Dr. Manuel Gea González, Mexico City, Mexico
Departamento de Producción Agrícola Y Animal, UAM-Unidad Xochimilco, Calzada del Hueso 1100 Col. Villa Quietud, Delegación Coyoacán, CP 04960, Mexico
División Académica de Ciencias Biológicas, Laboratorio de Ecología del Paisaje y Cambio Global, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, Mexico
Departamento de Biología Molecular e Histocompatibilidad, Hospital General Dr. Manuel Gea González, Mexico City, Mexico
Departamento de Parasitología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico
All Open Access, Gold
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