Oligomerization of 10,16-dihydroxyhexadecanoic acid and methyl 10,16-dihydroxyhexadecanoate catalyzed by lipases


Por: Gómez-Patiño M.B., Cassani J., Jaramillo-Flores M.E., Zepeda-Vallejo L.G., Sandoval G., Jimenez-Estrada M., Arrieta-Baez D.

Publicada: 1 ago 2013
Resumen:
The main monomer of tomato cuticle, 10,16-dihydroxyhexadecanoic acid (10,16-DHPA) and its methyl ester derivative (methyl-10,16- dihydroxyhexadecanote; methyl-10,16-DHHD), were used to study their oligomerization reactions catalyzed by five lipases: Candida antarctica lipase B (CAL-B), Rhizomucor miehei lipase (RM), Thermomyces lanuginosus lipase (TL), Pseudomonas cepacia lipase (PCL) and porcine pancreatic lipase (PPL). For 10,16-DHPA, optimum yields were obtained at 60 °C using toluene and 2-methyl-2-butanol (2M2B) as solvent, while for methyl-10,16-DHHD the bests yields were obtained in toluene and acetonitrile. Both reactions leaded to linear polyesters according to the NMR and FT-IR analysis, and there was no data indicating the presence of branched polymers. Using optimized conditions, poly(10,16-DHPA) and poly(methyl-10,16-DHHD) with Mw = 814 and Mn = 1,206 Da, and Mw = 982 and Mn = 860 Da, respectively, were formed according to their MALDI-TOF MS and ESI-MS data. The self-assembly of the polyesters obtained were analyzed by AFM. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

Filiaciones:
Gómez-Patiño M.B.:
 Instituto Politécnico Nacional - ENCB, Carpio y Plan de Ayala S/N, Col. Casco de Santo Tomas, México, D.F., CP 11340, Mexico

Cassani J.:
 Departamento de Sistemas Biológicos, Universidad Autónoma Metropolitana Unidad Xochimilco, Calz. del Hueso No.1100, Col. Villa Quietud, México, D.F., CP 04960, Mexico

Jaramillo-Flores M.E.:
 Instituto Politécnico Nacional - ENCB, Carpio y Plan de Ayala S/N, Col. Casco de Santo Tomas, México, D.F., CP 11340, Mexico

Zepeda-Vallejo L.G.:
 Instituto Politécnico Nacional - ENCB, Carpio y Plan de Ayala S/N, Col. Casco de Santo Tomas, México, D.F., CP 11340, Mexico

Sandoval G.:
 CIATEJ, Av. Normalistas 800, Guadalajara, Jalisco 42270, Mexico

Jimenez-Estrada M.:
 Univ Nacl Autonoma Mexico, Inst Quim, Dept Prod Nat, Mexico City 04510, DF, Mexico

Arrieta-Baez D.:
 Instituto Politécnico Nacional - CNMN, Unidad Profesional Adolfo López Mateos, Calle Luis Enrique Erro s/n, Col. Zacatenco, México D.F., CP 07738, Mexico
ISSN: 14203049
Editorial
MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, Suiza
Tipo de documento: Article
Volumen: 18 Número: 8
Páginas: 9317-9333
WOS Id: 000330304100040
ID de PubMed: 23921794
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