Seasonal effect on chemical composition and biological activities of Sonoran propolis
Por:
Valencia D., Alday E., Robles-Zepeda R., Garibay-Escobar A., Galvez-Ruiz J.C., Salas-Reyes M., Jiménez-Estrada M., Velazquez-Contreras E., Hernandez J., Velazquez C.
Publicada:
15 mar 2012
Resumen:
Propolis is widely used as a folk medicine and as a constituent of health foods in many parts of the world. The main purpose of this study was to evaluate the seasonal effect on the chemical composition and biological activities (antiproliferative and antioxidant activities) of Sonoran propolis (Mexico). Propolis was collected during all four seasons of the year and chemical composition, antiproliferative, and free-radical scavenging activities of collected propolis were evaluated by HPLC, MTT, and DPPH assays, respectively. The relative abundance of the main chemical constituents of propolis was similar in all propolis samples analysed. In contrast, significant differences were observed in their antiproliferative activity in the B-cell lymphoma cancer cell line M12.C3.F6. Propolis collected in the spring showed the highest inhibitory effect on the growth of cancer cells. All propolis samples had weak free-radical scavenging activity. Our results indicate that season had a significant effect on the antiproliferative properties of Sonoran propolis. © 2011 Elsevier Ltd. All rights reserved.
Filiaciones:
Valencia D.:
Department of Polymers and Materials (DIPM), University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
Alday E.:
Department of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
Robles-Zepeda R.:
Department of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
Garibay-Escobar A.:
Department of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
Galvez-Ruiz J.C.:
Department of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
Salas-Reyes M.:
Unidad de Servicios de Apoyo en Resolución Analítica, Universidad Veracruzana, Apdo. Postal 575, Xalapa, Ver., Mexico
Jiménez-Estrada M.:
Univ Nacl Autonoma Mexico, Inst Quim, Lab Prod Nat, Mexico City 04510, DF, Mexico
Velazquez-Contreras E.:
Department of Polymers and Materials (DIPM), University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
Hernandez J.:
Unidad de Servicios de Apoyo en Resolución Analítica, Universidad Veracruzana, Apdo. Postal 575, Xalapa, Ver., Mexico
Velazquez C.:
Department of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora 83000, Mexico
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