Moderate physical activity diminishes oxidative stress and the inflammatory process in elderly
Por:
Rosado-Perez, J, Santiago-Osorio, E, Ortiz, R, Mendoza-Nunez, VM
Publicada:
1 ene 2011
Categoría:
Medicine (miscellaneous)
Resumen:
Background: Physical activity has been linked with health in humans. However, several studies have cited that high physical activity could constitute a risk factor for oxidative stress (OxS) and chronic inflammation (CI). Objective: The aim of this study was to determine the effect of moderate physical activity on OxS and CI markers in elderly Mexicans. Methods: We carried out a cross-sectional and comparative study in a sample of 56 healthy elderly persons as follows: i) sedentary subjects (<= 2 metabolic equivalent tasks [METS]) in 30 subjects aged 68 +/- 7 years, and ii) moderate physical activity (3-6 METS) in 26 subjects 63 +/- 8 years of age. We measured plasmatic lipoperoxides, superoxide dismutase, glutathione peroxidase, and total antioxidant status. Also, it was measured, the inflammatory markers interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-alpha). Results: We found a statistically significant positive correlation between METS and the oxidative stress score (OxS
Filiaciones:
Rosado-Perez, J:
Univ Nacl Autonoma Mexico, Unidad Invest Gerontol, FES ZARAGOZA, Mexico City, DF, Mexico
Santiago-Osorio, E:
Univ Nacl Autonoma Mexico, Lab Biol Celular & Mol Canc, FES Zaragoza, UIDCC, Mexico City, DF, Mexico
Ortiz, R:
Univ Autonama Metropolitana Iztapalapa Apdo, Dept Ciencias Salud, Mexico City, DF, Mexico
Mendoza-Nunez, VM:
Univ Nacl Autonoma Mexico, Unidad Invest Gerontol, FES ZARAGOZA, Mexico City, DF, Mexico
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