Role of ischemic preconditioning in liver surgery and hepatic transplantation
Por:
Montalvo-Jave E.E., Pina, E, Montalvo-Arenas C., Urrutia R., Benavente-Chenhalls L., Pena-Sanchez, J, Geller D.A.
Publicada:
1 nov 2009
Resumen:
Introduction The purpose of this review is to summarize intraoperative surgical strategies available to decrease ischemiareperfusion injury associated with liver resection and liver transplantation. Material and method We conducted a critical review of the literature evaluating the potential applications of hepatic ischemic preconditioning (IPC) for hepatic resection surgery and liver transplantation. In addition, we provide a basic bench-to-bedside summary of the liver physiology and cell signaling mechanisms that account for the protective effects seen with hepatic IPC. © 2009 The Society for Surgery of the Alimentary Tract.
Filiaciones:
Montalvo-Jave E.E.:
Univ Nacl Autonoma Mexico, Fac Med, Dept Bioquim, Mexico City 04510, DF, Mexico
Univ Nacl Autonoma Mexico, Fac Med, Dept Cirugia, Mexico City 04510, DF, Mexico
Pina, E:
Univ Nacl Autonoma Mexico, Fac Med, Dept Bioquim, Mexico City 04510, DF, Mexico
Montalvo-Arenas C.:
Univ Nacl Autonoma Mexico, Fac Med, Dept Biol Celular & Tisular, Mexico City 04510, DF, Mexico
Urrutia R.:
Gastrointestinal Research Unit, Mayo Clinic, Rochester, MN, United States
Benavente-Chenhalls L.:
Department of Gastrointestinal and General Surgery, Mayo Clinic, Rochester, MN, United States
Pena-Sanchez, J:
Univ Nacl Autonoma Mexico, Inst Invest Biomed, Dept Biol Mol, Mexico City, DF, Mexico
Geller D.A.:
Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, United States
Thomas E. Starzl Transplantation Institute, University of Pittsburgh, 3459 Fifth Avenue, MUH 7 South, Pittsburgh, PA 15213, United States
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