Selective hydrogenation of the C=O bond of ketones using Ni(0) complexes with a chelating bisphosphine
Por:
Flores-Gaspar A., Pinedo-González P., Crestani M.G., Munoz-Hernandez, M, Morales-Morales D., Warsop B.A., Jones W.D., García J.J.
Publicada:
18 ago 2009
Resumen:
The nickel complexes [(dippe)Ni(eta(2)-O,C-benzophenone)] (2), [(dippe)Ni(eta(2)-O,C-4-methylbenzophenone)] (3), [(dippe)Ni(eta(2)-O,C-acetophenone)] (4), [(dippe)Ni(eta(2)-O,C-acetone)] (S), [(dippe)Ni(eta(2)O,C-fluorenone)] (6), [(dippe)Ni(eta(2)-O,C-di(2-pyridyl) ketone)] (7a) [(dippe)Ni(kappa(2)-N,N-di(2-pyridyl) ketone)] (7b), [(dippe)Ni(kappa(2)-O,O-2,2'-pyridil)] (8), [(dippe)Ni(kappa(2)-O,O-benzil)] (9a), and [((dippe)Ni)(2)(eta(2)-O,C-benzil)] (9b) were prepared by the reaction of [(dippe)Ni(mu-H)](2) (1) with the corresponding ketone or 1,2-diketone at room temperature. The structures of compounds 2, 6, 9a and 9b were confirmed by X-ray crystallography. The selective hydrogenation of the two types of substrates was undertaken using H(2), giving high conversions to the corresponding reduction products, either alcohols or alkanes. Tunable reaction conditions to promote the partial or total hydrogenation (hydrogenolysis) of the substrates are described. (C) 2009 Elsevier B.V. Al
Filiaciones:
Flores-Gaspar A.:
Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico
Pinedo-González P.:
Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico
Crestani M.G.:
Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico
Morales-Morales D.:
Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico
Warsop B.A.:
Department of Chemistry, University of Rochester, Rochester, NY 14627, United States
Jones W.D.:
Department of Chemistry, University of Rochester, Rochester, NY 14627, United States
García J.J.:
Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico
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