Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males


Por: Estrada-Reyes R., Ortiz-López P., Gutiérrez-Ortíz J., Martínez-Mota L.

Publicada: 25 jun 2009
Resumen:
Ethnopharmacological relevance: In folk medicine, Turnera diffusa Wild (Turnera diffusa, Turneraceae) is considered as an aphrodisiac, but its ability to restore copulation in sexually inhibited subjects has not been reported. Aim of the study: To determine whether Turnera diffusa recovers sexual behavior in sexually exhausted (SExh) male rats and to identify the main components in an aqueous extract. Materials and methods: SExh males were treated with Turnera diffusa, 20-80 mg/kg, yohimbine, 2 mg/kg, or vehicle. Results: Yohimbine and Turnera diffusa (80 mg/kg) significantly increased the percentage of males achieving one ejaculatory series and resuming a second one. In addition, Turnera diffusa significantly reduced the post-ejaculatory interval. These effects were not associated to an increase in locomotor activity or anxiety-like behaviors. The HPLC-ESI-MS analysis showed the presence of caffeine, arbutine, and flavonoids as the main compounds in the active extract. Conclusion: The

Filiaciones:
Estrada-Reyes R.:
 Laboratorio de Fitofarmacología, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada Mexico-Xochimilco 101, Col.San Lorenzo Huipulco, Del. Tlalpan, Mexico City 14370, Mexico

Ortiz-López P.:
 Laboratorio de Farmacología Conductual, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada Mexico-Xochimilco No. 101, Col.San Lorenzo Huipulco, Del. Tlalpan, Mexico City 14370, Mexico

Gutiérrez-Ortíz J.:
 Laboratorio de Farmacología Conductual, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada Mexico-Xochimilco No. 101, Col.San Lorenzo Huipulco, Del. Tlalpan, Mexico City 14370, Mexico

Martínez-Mota L.:
 Laboratorio de Farmacología Conductual, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada Mexico-Xochimilco No. 101, Col.San Lorenzo Huipulco, Del. Tlalpan, Mexico City 14370, Mexico
ISSN: 03788741
Editorial
ELSEVIER IRELAND LTD, ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND, Irlanda
Tipo de documento: Article
Volumen: 123 Número: 3
Páginas: 423-429
WOS Id: 000267557500009
ID de PubMed: 19501274

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