Histomorphology of Liver, Testicle and Body Fat in Farm Rabbits Fed with an Obesogenic Diet During the Peripuberal Period
Por:
Huerta N.G.M., Izquierdo A.C., Hernández J.A., Pérez F.I.F., Pérez-Martínez M.
Publicada:
1 ene 2015
Categoría:
Anatomy
Resumen:
Two groups were formed in order to evaluate the effect of an obesogenic
diet on body and liver weight, body fat accumulation and the histometric
characteristics of liver and testicles of New Zealand rabbits during the
peripuberal period. One group received a standard farm diet and the
other received a standard farm diet with canola oil added. During the
study, weight of both groups was recorded. At the end of the study, the
rabbits were euthanized and liver, testicles, and visceral, scapular and
scrotal fat were weighed. Tissue samples were obtained from liver and
testicles to carry out histometric analysis. Body weight, body mass
index, liver and visceral fat weight were significantly different
(P<0.01) in the obesogenic diet when compared to the control group.
Notwithstanding, there were no significant differences between both
groups in testicular weight, and scapular and scrotal fat (P>0.01).
Histometry of the liver of the obesogenic diet group showed the greater
total area and greater nucleus area of hepatocytes in the square lobe,
right lobe and left lobe medial segment (P<0.01). Histometry of both
testicles of individuals from the obesogenic diet group had a greater
germinal epithelial thickness and intertubular intersticium (P<0.01). It
is concluded that New Zealand male rabbits that received an obesogenic
diet during 12 weeks had a higher liver and body weight, as well as, an
important increased visceral fat. Furthermore, said diet caused
histometric changes in liver and testicles. This set confirms that the
domestic rabbit is a good model for the study of the body fat
accumulation process associated to the consumption of an obesogenic diet
and its effects on liver and testicles.
Filiaciones:
Huerta N.G.M.:
Departamento de Morfología, Universidad Nacional Autónoma de México, México D.F, Mexico
Izquierdo A.C.:
Departamento de Producción Agrícola y Animal, Universidad Autónoma Metropolitana Unidad Xochimilco, México D.F, Mexico
Hernández J.A.:
Área de anatomía veterinaria, Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico
Pérez F.I.F.:
Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico
Pérez-Martínez M.:
Departamento de Morfología, Universidad Nacional Autónoma de México, México D.F, Mexico
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