Increasing virulence and decreasing fungicide sensitivity in Phytophthora capsici after continuous metalaxyl-chlorothalonil exposure
Por:
Sevillano-Serrano, J, Larsen, J, Rojas-Rojas, FU, Vega-Arreguin, JC
Publicada:
1 nov 2024
Ahead of Print:
1 ago 2024
Resumen:
Several fungicide products with metalaxyl-chlorothalonil as the active ingredients are available in the Mexican market. Applying products containing this mixture of molecules is a common method that farmers choose to prevent damage caused to crops by Phytophthora capsici. Despite the efficacy of the mixture of metalaxyl-chlorothalonil in controlling the growth of this pathogen, their intensive use could contribute to the development of multidrug-resistant strains. Additionally, the dynamics of resistance to commercial metalaxyl-chlorothalonil-based fungicides and the virulence of P. capsici during continuous exposure are yet to be studied in detail. In this study, four continuous generations of P. capsici were exposed to two concentrations (5 and 100 mu gmL(-1)) of a commercial fungicide containing metalaxyl-chlorothalonil as the active ingredients. Changes in morphology, growth, and virulence were observed after the first interaction with the fungicide. However, in further generations exposed to the same amount of the product, the morphology and growth of P. capsici were partially restored, whereas its virulence was completely re-established. These results indicate a rapid adaptation to the metalaxyl-chlorothalonil mixture and highlight the importance of using different methods to control P. capsici and prevent the development of more virulent and multidrug-resistant strains.
Filiaciones:
Sevillano-Serrano, J:
Univ Nacl Autonoma Mexico, Escuela Nacl Estudios Super, Lab Ciencias AgroGenom, Unidad Leon,ENES Leon,UNAM, Blvd UNAM 2011, Leon 37684, Guanajuato, Mexico
Univ Nacl Autonoma Mexico, Escuela Nacl Estudios Super, Unidad Leon, Lab Nacl PlanTECC,ENES Leon,UNAM, Blvd UNAM 2011, Leon 37684, Guanajuato, Mexico
Larsen, J:
Univ Nacl Autonoma Mexico, Lab Nacl Innovac Ecotecnol Sustentabilidad, Antigua Carretera Patzcuaro 8701, Morelia 58190, Michoacan, Mexico
Univ Nacl Autonoma Mexico, Lab Agroecol, Inst Invest Ecosistemas & Sustentabilidad, Antigua Carretera Patzcuaro 8701, Morelia 58190, Michoacan, Mexico
Rojas-Rojas, FU:
Univ Nacl Autonoma Mexico, Escuela Nacl Estudios Super, Lab Ciencias AgroGenom, Unidad Leon,ENES Leon,UNAM, Blvd UNAM 2011, Leon 37684, Guanajuato, Mexico
Univ Nacl Autonoma Mexico, Escuela Nacl Estudios Super, Unidad Leon, Lab Nacl PlanTECC,ENES Leon,UNAM, Blvd UNAM 2011, Leon 37684, Guanajuato, Mexico
Vega-Arreguin, JC:
Univ Nacl Autonoma Mexico, Escuela Nacl Estudios Super, Lab Ciencias AgroGenom, Unidad Leon,ENES Leon,UNAM, Blvd UNAM 2011, Leon 37684, Guanajuato, Mexico
Univ Nacl Autonoma Mexico, Escuela Nacl Estudios Super, Unidad Leon, Lab Nacl PlanTECC,ENES Leon,UNAM, Blvd UNAM 2011, Leon 37684, Guanajuato, Mexico
hybrid, All Open Access
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