Aminotransferases in Relation to the Severity of Dengue: A Systematic Review
Por:
Kalluru, PKR, Mamilla, M, Valisekka, SS, Mandyam, S, Martinez, EC, Posani, S, Sharma, S, Gopavaram, RR, Gargi, B, Gaddam, A, Reddy, S
Publicada:
24 may 2023
Resumen:
A systematic review was conducted to investigate the relationship between aminotransferases and the severity of dengue infection, which is a prevalent and significant infection in tropical and subtropical regions. Aminotransferases are enzymes that are often elevated in dengue due to the liver's physiological and immunological response to the infection. This review focused on analyzing various studies that examined the correlation between aminotransferase levels and the severity of dengue. Extensive literature searches were performed using ("dengue*" OR "dengue fever*" OR "dengue haemorrhagic fever*" OR "dengue shock syndrome*") AND ("alanine aminotransferase*" OR "aspartate aminotransferase*") on PubMed. The selected articles were thoroughly reviewed, encompassing epidemiology, pathogenesis, and clinical manifestations of dengue. The consistent findings across the studies indicated that aminotransferases can serve as predictive markers for dengue severity. Therefore, early assessment of liver enzyme levels is crucial in dengue cases, and elevated levels should be closely monitored to prevent adverse outcomes.
Filiaciones:
Kalluru, PKR:
Sri Venkateswara Med Coll, Internal Med, Tirupati, India
Mamilla, M:
Sri Venkateswara Med Coll, Internal Med, Tirupati, India
Valisekka, SS:
Univ Minnesota, Internal Med, Sch Med, Minneapolis, MN USA
Mandyam, S:
Southeast Hlth Med Ctr, Internal Med, Dothan, AL USA
Martinez, EC:
Univ Nacl Autonoma Mexico, Biomed Informat, Mexico City, Mexico
Posani, S:
Sri Devaraj Urs Med Coll, Internal Med, Kothagudem, India
Sharma, S:
Dnipropetrovsk State Med Acad, Internal Med, Dnipro, Ukraine
Gopavaram, RR:
Dnipropetrovsk State Med Acad, Internal Med, Dnipro, Ukraine
Gargi, B:
Univ Alabama Birmingham, Publ Hlth, Sch Med, Brimingham, AL USA
Gaddam, A:
Siddhartha Med Coll, Internal Med, Vijayawada, India
Reddy, S:
Malla Reddy Inst Med Sci, Internal Med, Hyderabad, Pakistan
Green Published, gold
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