Myristicin: From its biological effects in traditional medicine in plants to preclinical studies and use as ecological remedy in plant protection
Por:
Ramírez-Alarcón, K, Martorell, M, Gürer, ES, Laher, I, Lam, HL, Mohieldin, EAM, Muddathir, AM, Akram, M, Iqbal, M, Shafique, H, Leyva-Gómez, G, Shaheen, S, Kumar, M, Sharifi-Rad, J, Amarowicz, R, Butnariu, M
Publicada:
1 jun 2023
Categoría:
Food science
Resumen:
Myristicin is an allylbenzene and a major key constituent of many plant species, such as Myristica fragrans Houtt. (nutmeg), Foeniculum vulgare Mill. (fennel), and Petroselinum crispum (Mill.) Fuss (parsley). Their plant parts have been used in traditional medicine and as a flavoring seasoning for cooking but, and as biopesticides with natural compounds. Myristicin has been related with several biological effects, such as anticarcinogenic, anti-inflammatory, antimicrobial, antioxidant, antidiabetic, analgesic, and hepatoprotective. The traditional uses include the treatment of complications related to gastrointestinal tract, respiratory system, and gynecological disorders. However, several studies have been reported contraindications associated to high dose consumption of myristicin. This review summarizes the biological activities of myristicin and myristicin-rich plants, toxicological effects along with its bioavailability, and metabolism. In addition, their traditional uses and their role as ecological remedy in plants protection has been reviewed. Nutmeg is the myristicin-rich plant with more pharmacological effects reported but also with most contraindication and toxically reports.
The aim of the present review is to highlight the traditional uses and pharmacological activities of myristicin-rich plants along with their contraindications and bioavailability.image
Filiaciones:
Ramírez-Alarcón, K:
Univ Concepcion, Fac Pharm, Dept Nutr & Dietet, Concepcion, Chile
Martorell, M:
Univ Concepcion, Fac Pharm, Dept Nutr & Dietet, Concepcion, Chile
Univ Concepcion, Ctr Hlth Living, Concepcion, Chile
Univ Concepcion, Unidad Desarrollo Tecnol, UDT, Concepcion, Chile
Univ Concepcion, Ctr Hlth Living, Concepcion 4070386, Chile
Gürer, ES:
Sivas Cumhuriyet Univ, Fac Pharm, Dept Pharmacognosy, Sivas, Turkiye
Laher, I:
Univ British Columbia, Fac Med, Dept Anesthesiol Pharmacol & Therapeut, Vancouver, BC, Canada
Lam, HL:
Univ Hong Kong, LKS Fac Med, Hong Kong, Peoples R China
Mohieldin, EAM:
Univ Sci & Technol, Fac Pharm, Omdurman, Sudan
Muddathir, AM:
Univ Khartoum, Fac Agr, Dept Hort, Shambat, Khartoum North, Sudan
Akram, M:
Govt Coll Univ Faisalabad, Dept Eastern Med, Faisalabad, Pakistan
Iqbal, M:
Dow Univ Hlth Sci, Inst Hlth Management, Karachi, Pakistan
Shafique, H:
Govt Coll Univ Faisalabad, Dept Eastern Med, Faisalabad, Pakistan
Leyva-Gómez, G:
Univ Nacl Autonoma Mexico, Fac Quim, Dept Farm, Mexico City, Mexico
Shaheen, S:
Dept Plant Sci, LCWU, Lahore, Pakistan
Kumar, M:
Cent Inst Res Cotton Technol, Chem & Biochem Proc Div, ICAR, Mumbai, India
Cent Inst Res Cotton Technol, Chem & Biochem Proc Div, ICAR, Mumbai 400019, India
Sharifi-Rad, J:
Univ Azuay, Fac Med, Cuenca, Ecuador
Univ Azuay, Fac Med, Cuenca 14008, Ecuador
Amarowicz, R:
Polish Acad Sci, Olsztyn, Poland
Butnariu, M:
Univ Life Sci King Michael I Timisoara, Calea Aradului, Timis, Romania
Univ Life Sci King Michael I Timisoara, Calea Aradului 119, Timis 300645, Romania
gold, All Open Access; Gold Open Access
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