Unraveling the diversity of Trypanosoma species from Central Mexico: Molecular confirmation on the presence of Trypanosoma dionisii and novel Neobat linages


Por: Juárez-Gabriel J., Alegría-Sánchez D., Yáñez-Aguirre D., Grostieta E., Álvarez-Castillo L., Torres-Castro M., Aréchiga-Ceballos N., Moo-Llanes D.A., Alves F.M., Pérez-Brígido C.D., Aguilar-Tipacamú G., López González C.A., Becker I., Pech-Canché J.M., Colunga-Salas P., Sánchez-Montes S.

Publicada: 1 ene 2024 Ahead of Print: 1 ene 2024
Resumen:
Bats are one of the groups of mammals with the highest number of associated Trypanosoma taxa. There are 50 Trypanosoma species and genotypes infecting more than 75 species of bats across five continents. However, in Mexico, the inventory of species of the genus Trypanosoma associated with bats is limited to only two species (Trypanosoma vespertilionis and Trypanosoma cruzi) even though 140 species of bats inhabit this country. Specifically, 91 bat species have been recorded in the state of Veracruz, but records of trypanosomatids associated with this mammalian group are absent. Due to the complex Trypanosoma–bat relationship, the high diversity of bat species in Veracruz, as well as the lack of records of trypanosomatids associated with bats for this state, the aim of this work was to analyze the diversity of species of the genus Trypanosoma and their presence from a bat community in the central area of the state of Veracruz, Mexico. During the period of January to August 2022 in the Tequecholapa Environmental Management Unit where bats were collected using mist nets and blood samples were obtained from their thumbs. We extracted genetic material and amplified a fragment of 800 bp of the 18S ribosomal gene of the genus Trypanosoma by conventional PCR. The positive amplicons were sequenced, and phylogenetic reconstruction was performed to identify the parasite species. A total of 285 bats (149?, 136?) belonging to 13 species from 10 genera and a single family (Phyllostomidae) were collected. Twenty-three specimens from six species tested positive for the presence of Trypanosoma dionisii, Trypanosoma sp. Neobat 4, and a potential novelty species provisionally named as Trypanosoma sp. Neobat 6. The results of the present work increase the number of species of the genus Trypanosoma infecting bats in Mexico and in the Neotropical region. © 2023

Filiaciones:
Juárez-Gabriel J.:
 Maestría en Ciencias del Ambiente, Facultad de Ciencias Biológicas y Agropecuarias región Tuxpan, Universidad Veracruzana, Tuxpan de Rodriguez Cano, Veracruz, Mexico

 Centro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

Alegría-Sánchez D.:
 Facultad de Ciencias Biológicas y Agropecuarias región Peñuela, Universidad Veracruzana, Amatlán de los Reyes, Veracruz, Mexico

Yáñez-Aguirre D.:
 Facultad de Ciencias Biológicas y Agropecuarias región Peñuela, Universidad Veracruzana, Amatlán de los Reyes, Veracruz, Mexico

Grostieta E.:
 Centro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

Álvarez-Castillo L.:
 Posgrado en Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Av. Ciudad Universitaria 3000, C.P. 04510, Coyoacán, Ciudad de México, Mexico

Torres-Castro M.:
 Laboratorio de Zoonosis y Otras Enfermedades Transmitidas por Vector, Centro de Investigaciones Regionales “Dr. Hideyo Noguchi”, Universidad Autónoma de Yucatán, Yucatán, Mérida, Mexico

Aréchiga-Ceballos N.:
 Dirección de Diagnóstico y Referencia, Instituto de Diagnóstico y Referencia Epidemiológicos Dr. Manuel Martínez Báez, Mexico City, Mexico

Moo-Llanes D.A.:
 Grupo de Arbovirosis y Zoonosis, Centro Regional de Investigación en Salud Pública, Instituto Nacional de Salud Pública, Chiapas, Tapachula, Mexico

Alves F.M.:
 Laboratory of Trypanosomatid Biology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Rio de Janeiro, Brazil

Pérez-Brígido C.D.:
 Hospital Veterinario, Facultad de Ciencias Biológicas y Agropecuarias, región Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz, Mexico

Aguilar-Tipacamú G.:
 CA. Ecología y Diversidad Faunística, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Mexico

López González C.A.:
 CA. Ecología y Diversidad Faunística, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Mexico

Becker I.:
 Centro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

Pech-Canché J.M.:
 Laboratorio de Vertebrados Terrestres, Facultad de Ciencias Biológicas y Agropecuarias región Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz, Mexico

Colunga-Salas P.:
 Centro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

 Instituto de Biotecnología y Ecología Aplicada, Universidad Veracruzana, Xalapa de Enríquez, Veracruz, Mexico

Sánchez-Montes S.:
 Centro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

 Laboratorio de Diagnóstico, Facultad de Ciencias Biológicas y Agropecuarias región Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz, Mexico
ISSN: 0001706X
Editorial
Elsevier, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, Países Bajos
Tipo de documento: Article
Volumen: 251 Número:
Páginas:
WOS Id: 001166144300001
ID de PubMed: 38157924