Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
Por:
Ortiz-Mendoza N., Martínez-Gordillo M.J., Martínez-Ambriz E., Basurto-Peña F.A., González-Trujano M.E., Aguirre-Hernández E.
Publicada:
1 ene 2023
Resumen:
Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect information on traditional uses through ethnobotanical, pharmacological, and phytochemical information of the subfamily Nepetoideae related to inflammatory diseases. UNAM electronic resources were used to obtain the information. The analysis of the most relevant literature was compiled and organised in tables. From this, about 106 species of the subfamily are traditionally recognised to alleviate chronic pain associated with inflammation. Pharmacological studies have been carried out in vitro and in vivo on approximately 308 species belonging to the genera Salvia, Ocimum, Thymus, Mentha, Origanum, Lavandula, and Melissa. Phytochemical and pharmacological evaluations have been performed and mostly prepared as essential oil or high polarity extracts, whose secondary metabolites are mainly of a phenolic nature. Other interesting and explored metabolites are diterpenes from the abietane, clerodane, and kaurane type; however, they have only been described in some species of the genera Salvia and Isodon. This review reveals that the Nepetoideae subfamily is an important source for therapeutics of the inflammatory process. © 2023 by the authors.
Filiaciones:
Ortiz-Mendoza N.:
Laboratorio de Productos Naturales, Departamento de Ecología y Recursos Naturales, Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Posgrado en Ciencias Biológicas, Unidad de Posgrado, Ciudad Universitaria Coyoacán, Edificio D, 1° Piso, Circuito de Posgrados, Mexico City, 04510, Mexico
Martínez-Gordillo M.J.:
Departamento de Biología Comparada, Herbario de la Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
Martínez-Ambriz E.:
Instituto de Ecología, A.C., Red de Biodiversidad y Sistemática, Veracruz, Xalapa, 91073, Mexico
Basurto-Peña F.A.:
Instituto de Biología, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
González-Trujano M.E.:
Laboratorio de Neurofarmacología de Productos Naturales, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City, 14370, Mexico
Aguirre-Hernández E.:
Laboratorio de Productos Naturales, Departamento de Ecología y Recursos Naturales, Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico
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