Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study


Por: Tejeda-Castellanos, Xochiquetzalli, Sanchez-Medina, Carlos Maximiliano, Marquez-Gonzalez, Horacio, Alaniz-Arcos, Jose Luis, Ortiz-Cornejo, Ma. Elena, Brito-Suarez, Juliette Marie, Juarez-Villegas, Luis, Gutierrez-Camacho, Claudia

Publicada: 16 oct 2023
Categoría: Pediatrics, perinatology and child health

Resumen:
AimWe evaluated fine motor skills; precision, motor integration, manual dexterity, and upper-limb coordination according to sex and risk stratification in children with Acute Lymphoblastic Leukaemia (ALL).MethodsWe evaluated twenty-nine children in the maintenance phase aged 6 to 12 years with the Bruininks-Oseretsky Test of Motor Proficiency-second edition (BOT-2), and sex and age-specific norm values of BOT-2 were used to compare our results.ResultsWe found lower scores on the upper-limb coordination subtest, p = 0.003 and on the manual coordination composite, p = 0.008, than normative values. Most boys performed ``average'' on both the subtests and the composites, but girls showed lower scores with a mean difference of 7.69 (95%CI; 2.24 to 3.14), p = 0.009. Girls' scale scores on the upper-limb coordination subtest were lower than normative values, with mean difference 5.08 (95%CI; 2.35 to 7.81), p = 0.006. The mean standard score difference in high-risk patients was lower than normative on the manual coordination composite, 8.18 (95%CI; 2.26 to 14.1), p = 0.015. High-risk children also performed below the BOT-2 normative on manual dexterity 2.82 (95%CI; 0.14 to 5.78), p = 0.035 and upper limb coordination subtest 4.10 (95%CI; 1.13 to 7.05), p = 0.028. We found a decrease in fine motor precision in children with a higher BMI, rho= -0.87, p = 0.056 and a negative correlation between older age and lower manual dexterity, r= -0.41 p = 0.026; however, we did not find any correlation with the weeks in the maintenance phase.ConclusionsFine motor impairments are common in children with ALL in the maintenance phase; it is important to identify these impairments to early rehabilitation.

Filiaciones:
Tejeda-Castellanos, Xochiquetzalli:
 Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de México, Dr. Márquez 162 Colonia Doctores, Mexico City, 06720, Mexico

 Univ Nacl Autonoma Mexico, Fac Med, Physiotherapy Res Unit, Dr Marquez 162 Colonia Doctores, Mexico City 06720, Mexico

Sanchez-Medina, Carlos Maximiliano:
 Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de México, Dr. Márquez 162 Colonia Doctores, Mexico City, 06720, Mexico

 Univ Nacl Autonoma Mexico, Fac Med, Physiotherapy Res Unit, Dr Marquez 162 Colonia Doctores, Mexico City 06720, Mexico

Marquez-Gonzalez, Horacio:
 Research Department, Hospital Infantil de México Federico Gómez, Mexico City, Mexico

 Hosp Infantil Mexico Dr Federico Gomez, Res Dept, Mexico City, Mexico

Alaniz-Arcos, Jose Luis:
 Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de México, Dr. Márquez 162 Colonia Doctores, Mexico City, 06720, Mexico

 Univ Nacl Autonoma Mexico, Fac Med, Physiotherapy Res Unit, Dr Marquez 162 Colonia Doctores, Mexico City 06720, Mexico

Ortiz-Cornejo, Ma. Elena:
 Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de México, Dr. Márquez 162 Colonia Doctores, Mexico City, 06720, Mexico

 Univ Nacl Autonoma Mexico, Fac Med, Physiotherapy Res Unit, Dr Marquez 162 Colonia Doctores, Mexico City 06720, Mexico

Brito-Suarez, Juliette Marie:
 Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de México, Dr. Márquez 162 Colonia Doctores, Mexico City, 06720, Mexico

 Univ Nacl Autonoma Mexico, Fac Med, Physiotherapy Res Unit, Dr Marquez 162 Colonia Doctores, Mexico City 06720, Mexico

Juarez-Villegas, Luis:
 Haematology and oncology department of the Hospital Infantil de Mexico, Federico Gómez, Mexico City, Mexico

 Hosp Infantil Mexico Dr Federico Gomez, Haematol & Oncol Dept, Mexico City, Mexico

Gutierrez-Camacho, Claudia:
 Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de México, Dr. Márquez 162 Colonia Doctores, Mexico City, 06720, Mexico

 Univ Nacl Autonoma Mexico, Fac Med, Physiotherapy Res Unit, Dr Marquez 162 Colonia Doctores, Mexico City 06720, Mexico
ISSN: 14712431





BMC PEDIATRICS
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BIOMED CENTRAL LTD, 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 23 Número: 1
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WOS Id: 001086711300007
ID de PubMed: 37845644
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