Study of Polyvinyl Alcohol Hydrogels Applying Physical-Mechanical Methods and Dynamic Models of Photoacoustic Signals
Por:
Ramirez-Chavarria, Roberto G., Perez-Pacheco, Argelia, Teran, Emiliano, Quispe-Siccha, Rosa M.
Publicada:
1 sep 2023
Resumen:
This study aims to analyze the physical-mechanical properties and
dynamic models of tissue-simulating hydrogels, specifically the
photoacoustic (PA) response signals, by varying the concentrations of
polyvinyl alcohol (PVA) and molecular weight (MW). A state-space model
(SSM) is proposed to study the PVA hydrogels to retrieve the PA-related
signal's damping ratio and natural frequency. Nine box-shaped PVA
hydrogels containing saline solution were used, with five concentrations
of PVA (7, 9, 12, 15, 20%) for MW1 and four for MW2. The results
indicated that the concentration of PVA and MW played an important role
in the PA wave's amplitude, arrival time, and speed of sound over the
hydrogels. The SSM parameters showed that increasing PVA and MW
concentrations improved the hydrogels' ability to absorb and transfer
energy under the PA effect. These parameters were also found to be
correlated with density and modulus of elasticity. Additionally, the
concentrations of PVA and MW affected the absorption and optical
scattering coefficients. The physical-mechanical properties, including
porosity, density, and modulus of elasticity, improved as the
concentration of PVA and MW increased. The ultimate goal of this study
is to develop hydrogels as phantoms that can be used for tissue
simulation and imaging.
Filiaciones:
Ramirez-Chavarria, Roberto G.:
Engineering Institute, National Autonomous University of Mexico, Mexico City, 04510, Mexico
Perez-Pacheco, Argelia:
Research and Technological Development Unit, Research Department, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico City, 06726, Mexico
Teran, Emiliano:
Faculty of Physical-Mathematical Sciences, Autonomous University of Sinaloa, Sinaloa, Culiacan, 80040, Mexico
Quispe-Siccha, Rosa M.:
Research and Technological Development Unit, Research Department, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico City, 06726, Mexico
Green Submitted, Green Published, gold
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