Genomic evidence for the Pleistocene and recent population history of Native Americans
Por:
Raghavan M., Steinrücken M., Harris K., Schiffels S., Rasmussen S., DeGiorgio M., Albrechtsen A., Valdiosera C., Ávila-Arcos M.C., Malaspinas A.-S., Eriksson A., Moltke I., Metspalu M., Homburger J.R., Wall J., Cornejo O.E., Moreno-Mayar J.V., Korneliussen T.S., Pierre T., Rasmussen M., Campos P.F., De Barros Damgaard P., Allentoft M.E., Lindo J., Metspalu E., Rodríguez-Varela R., Mansilla J., Henrickson C., Seguin-Orlando A., Malmstöm H., Stafford T., Jr., Shringarpure S.S., Moreno-Estrada A., Karmin M., Tambets K., Bergström A., Xue Y., Warmuth V., Friend A.D., Singarayer J., Valdes P., Balloux F., Leboreiro I., Vera J.L., Rangel-Villalobos H., Pettener D., Luiselli D., Davis L.G., Heyer E., Zollikofer C.P.E., Ponce De León M.S., Smith C.I., Grimes V., Pike K.-A., Deal M., Fuller B.T., Arriaza B., Standen V., Luz M.F., Ricaut F., Guidon N., Osipova L., Voevoda M.I., Posukh O.L., Balanovsky O., Lavryashina M., Bogunov Y., Khusnutdinova E., Gubina M., Balanovska E., Fedorova S., Litvinov S., Malyarchuk B., Derenko M., Mosher M.J., Archer D., Cybulski J., Petzelt B., Mitchell J., Worl R., Norman P.J., Parham P., Kemp B.M., Kivisild T., Tyler-Smith C., Sandhu M.S., Crawford M., Villems R., Smith D.G., Waters M.R., Goebel T., Johnson J.R., Malhi R.S., Jakobsson M., Meltzer D.J., Manica A., Durbin R., Bustamante C.D., Song Y.S., Nielsen R., Willerslev E.
Publicada:
1 ene 2015
Resumen:
How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model. © 2015, American Association for the Advancement of Science. All rights reserved.
Filiaciones:
Raghavan M.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Steinrücken M.:
Computer Science Division, University of California, Berkeley, Berkeley, CA 94720, United States
Department of Statistics, University of California, Berkeley, Berkeley, CA 94720, United States
Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA 01003, United States
Harris K.:
Department of Mathematics, University of California, Berkeley, Berkeley, CA 94720, United States
Schiffels S.:
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom
Rasmussen S.:
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet, Building 208, Kongens Lyngby, 2800, Denmark
DeGiorgio M.:
Departmentof Biology and Statistics, Pennsylvania State University, 502 Wartik Laboratory, University Park, PA 16802, United States
Albrechtsen A.:
Bioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200, Denmark
Valdiosera C.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Department of Archaeology and History, La Trobe University, Melbourne, VIC 3086, Australia
Ávila-Arcos M.C.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, United States
Malaspinas A.-S.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Eriksson A.:
Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, United Kingdom
Integrative Systems Biology Laboratory, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia
Moltke I.:
Bioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200, Denmark
Metspalu M.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Department of Evolutionary Biology, University of Tartu, Tartu, 51010, Estonia
Homburger J.R.:
Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, United States
Wall J.:
Institute for Human Genetics, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, United States
Cornejo O.E.:
School of Biological Sciences, Washington State University, Post Office Box 644236, Heald 429, Pullman, WA 99164, United States
Moreno-Mayar J.V.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Korneliussen T.S.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Pierre T.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Rasmussen M.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, United States
Campos P.F.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Centro de Investigación en Ciencias del Mar y Limnología/Centro Interdisciplinar de Investigação Marinha e Ambiental, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Rua dos Bragas 289, Porto, 4050-123, Portugal
De Barros Damgaard P.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Allentoft M.E.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Lindo J.:
Department of Anthropology, University of Illinois at Urbana-Champaign, 607 S. Mathews Avenue, Urbana, IL 61801, United States
Metspalu E.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Department of Evolutionary Biology, University of Tartu, Tartu, 51010, Estonia
Rodríguez-Varela R.:
Centro Mixto, Universidad Complutense de Madrid, Instituto de Salud Carlos III de Evolución y Comportamiento Humano, Madrid, Spain
Mansilla J.:
Instituto Nacional de Antropología e Historia, Moneda 13, Centro, Cuauhtémoc, Mexico City, 06060, Mexico
Henrickson C.:
University of Utah, Department of Anthropology, 270 S 1400 E, Salt Lake City, UT 84112, United States
Seguin-Orlando A.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Malmstöm H.:
Department of Evolutionary Biology and Science for Life Laboratory, Uppsala University, Norbyvägen 18D, Uppsala, SE-752 36, Sweden
Stafford T.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Acceleration Mass Spectrometry 14C Dating Centre, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, Aarhus, 8000, Denmark
Jr.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Acceleration Mass Spectrometry 14C Dating Centre, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, Aarhus, 8000, Denmark
Shringarpure S.S.:
Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, United States
Moreno-Estrada A.:
Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, United States
Laboratorio Nacional de Genómica para la Biodiversidad (LANGEBIO), Centro de Investigación y de Estudios Avanzados, Irapuato, Guanajuato 36821, Mexico
Karmin M.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Department of Evolutionary Biology, University of Tartu, Tartu, 51010, Estonia
Tambets K.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Bergström A.:
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom
Xue Y.:
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom
Warmuth V.:
Genetics Institute, University College London, Gower Street, London, WC1E 6BT, United Kingdom
Evolutionsbiologiskt Centrum, Norbyvägen 18D, Uppsala, 75236, Sweden
Friend A.D.:
Department of Geography, University of Cambridge, Downing Place, Cambridge, CB2 3EN, United Kingdom
Singarayer J.:
Centre for Past Climate Change, Department of Meteorology, University of Reading, Earley Gate, Post Office Box 243, Reading, United Kingdom
Valdes P.:
School of Geographical Sciences, University Road, Clifton, Bristol, BS8 1SS, United Kingdom
Balloux F.:
Genetics Institute, University College London, Gower Street, London, WC1E 6BT, United Kingdom
Leboreiro I.:
Instituto Nacional de Antropología e Historia, Moneda 13, Centro, Cuauhtémoc, Mexico City, 06060, Mexico
Vera J.L.:
Escuela Nacional de Antropología e Historia, Periférico Sur y Zapote s/n Colonia Isidro Fabela, Tlalpan, Isidro Fabela, Mexico City, 14030, Mexico
Rangel-Villalobos H.:
Instituto de Investigación en Genética Molecular, Universidad de Guadalajara, Ocotlán, Mexico
Pettener D.:
Dipartimento di Scienze Biologiche, Geologiche e Ambientali (BiGeA), Università di Bologna, Via Selmi 3, Bologna, 40126, Italy
Luiselli D.:
Dipartimento di Scienze Biologiche, Geologiche e Ambientali (BiGeA), Università di Bologna, Via Selmi 3, Bologna, 40126, Italy
Davis L.G.:
Department of Anthropology, Oregon State University, 238 Waldo Hall, Corvallis, OR 97331, United States
Heyer E.:
Museum National d'Histoire Naturelle, CNRS, Université Paris 7 Diderot, Paris, France
Zollikofer C.P.E.:
Anthropological Institute and Museum, University of Zürich, Winterthurerstrasse 190, Zürich, 8057, Switzerland
Ponce De León M.S.:
Anthropological Institute and Museum, University of Zürich, Winterthurerstrasse 190, Zürich, 8057, Switzerland
Smith C.I.:
Department of Archaeology and History, La Trobe University, Melbourne, VIC 3086, Australia
Grimes V.:
Department of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, A1C 5S7, Canada
Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, 04103, Germany
Pike K.-A.:
Department of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, A1C 5S7, Canada
Deal M.:
Department of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, A1C 5S7, Canada
Fuller B.T.:
Department of Earth System Science, University of California, Irvine, Keck Carbon Cycle Accelerator Mass Spectrometry Group, B321 Croul Hall, Irvine, CA 92697, United States
Arriaza B.:
Instituto de Alta Investigación, Universidad de Tarapacá, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile
Standen V.:
Departamento de Antropologia, Universidad de Tarapacá, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile
Luz M.F.:
Fundação Museu do Homem Americano, Centro Cultural Sérgio Motta, Campestre, Sao Raimundo Nonato, 64770-000, Brazil
Ricaut F.:
Laboratoire d'Anthropologie Moléculaire et Imagérie de Synthèse UMR-5288, CNRS, Université de Toulouse, Toulouse, 31073, France
Guidon N.:
Fundação Museu do Homem Americano, Centro Cultural Sérgio Motta, Campestre, Sao Raimundo Nonato, 64770-000, Brazil
Osipova L.:
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, 630090, Russian Federation
Novosibirsk State University, 2 Pirogova Street, Novosibirsk, 630090, Russian Federation
Voevoda M.I.:
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, 630090, Russian Federation
Institute of Internal Medicine, Siberian Branch of RAS, 175/1 ul. B. Bogatkova, Novosibirsk, 630089, Russian Federation
Novosibirsk State University, Laboratory of Molecular Epidemiology and Bioinformatics, Novosibirsk, 630090, Russian Federation
Posukh O.L.:
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, 630090, Russian Federation
Novosibirsk State University, 2 Pirogova Street, Novosibirsk, 630090, Russian Federation
Balanovsky O.:
Vavilov Institute of General Genetics, Gubkina 3, Moscow, 119333, Russian Federation
Research Centre for Medical Genetics, Moskvorechie 1, Moscow, 115478, Russian Federation
Lavryashina M.:
Kemerovo State University, Krasnaya 3, Kemerovo, 650000, Russian Federation
Bogunov Y.:
Vavilov Institute of General Genetics, Gubkina 3, Moscow, 119333, Russian Federation
Khusnutdinova E.:
Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Prospekt Oktyabrya 71, Ufa, 450054, Russian Federation
Department of Genetics and Fundamental Medicine, Bashkir State University, Zaki Validi 32, Ufa, 450076, Russian Federation
Gubina M.:
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, 630090, Russian Federation
Balanovska E.:
Research Centre for Medical Genetics, Moskvorechie 1, Moscow, 115478, Russian Federation
Fedorova S.:
Department of Molecular Genetics, Yakut Scientific Centre of Complex Medical Problems, Sergelyahskoe Shosse 4, Yakutsk, 677010, Russian Federation
Laboratory of Molecular Biology, Institute of Natural Sciences, M. K. Ammosov North-Eastern Federal University, Yakutsk, 677000, Russian Federation
Litvinov S.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Prospekt Oktyabrya 71, Ufa, 450054, Russian Federation
Malyarchuk B.:
Institute of Biological Problems of the North, Russian Academy of Sciences, Portovaya Street 18, Magadan, 685000, Russian Federation
Derenko M.:
Institute of Biological Problems of the North, Russian Academy of Sciences, Portovaya Street 18, Magadan, 685000, Russian Federation
Mosher M.J.:
Department of Anthropology, Western Washington University, Bellingham, WA 98225, United States
Archer D.:
Department of Anthropology, Northwest Community College, 353 Fifth Street, 65Prince RupertBC V8J 3L6, Canada
Cybulski J.:
Canadian Museum of History, 100 Rue Laurier, Gatineau, QC K1A 0M8, Canada
University of Western Ontario, London, ON N6A 3K7, Canada
Simon Fraser University, Burnaby, BC V5A 1S6, Canada
Petzelt B.:
Metlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC V8J 3P6, Canada
Mitchell J.:
Metlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC V8J 3P6, Canada
Worl R.:
Sealaska Heritage Institute, 105 S. Seward Street, Juneau, AK 99801, United States
Norman P.J.:
Department of Structural Biology, Stanford University School of Medicine, D100 Fairchild Science Building, Stanford, CA 94305-5126, United States
Parham P.:
Department of Structural Biology, Stanford University School of Medicine, D100 Fairchild Science Building, Stanford, CA 94305-5126, United States
Kemp B.M.:
School of Biological Sciences, Washington State University, Post Office Box 644236, Heald 429, Pullman, WA 99164, United States
Department of Anthropology, Washington State University, Pullman, WA 99163, United States
Kivisild T.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Division of Biological Anthropology, University of Cambridge, Henry Wellcome Building, Fitzwilliam Street, Cambridge, CB2 1QH, United Kingdom
Tyler-Smith C.:
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom
Sandhu M.S.:
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom
Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH, United Kingdom
Crawford M.:
Laboratory of Biological Anthropology, University of Kansas, 1415 Jayhawk Boulevard, 622 Fraser Hall, Lawrence, KS 66045, United States
Villems R.:
Estonian Biocentre, Evolutionary Biology Group, Tartu, 51010, Estonia
Department of Evolutionary Biology, University of Tartu, Tartu, 51010, Estonia
Smith D.G.:
KSMolecular Anthropology Laboratory, Department of Anthropology, University of California, One Shields Avenue, Davis, 95616, United States
Waters M.R.:
Center for the Study of the First Americans, Texas A and M University, College Station, 77843-4352, United States
Department of Anthropology, Texas A and M University, College Station, TX 77843-4352, United States
Department of Geography, Texas A and M University, College Station, TX 77843-4352, United States
Goebel T.:
Center for the Study of the First Americans, Texas A and M University, College Station, 77843-4352, United States
Johnson J.R.:
Santa Barbara Museum of Natural History, 2559 Puesta del Sol, Santa Barbara, CA 93105, United States
Malhi R.S.:
Department of Anthropology, University of Illinois at Urbana-Champaign, 607 S. Mathews Avenue, Urbana, IL 61801, United States
Carle R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, United States
Jakobsson M.:
Department of Evolutionary Biology and Science for Life Laboratory, Uppsala University, Norbyvägen 18D, Uppsala, SE-752 36, Sweden
Meltzer D.J.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Department of Anthropology, Southern Methodist University, Dallas, TX 75275, United States
Manica A.:
Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, United Kingdom
Durbin R.:
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom
Bustamante C.D.:
Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, United States
Song Y.S.:
Computer Science Division, University of California, Berkeley, Berkeley, CA 94720, United States
Department of Statistics, University of California, Berkeley, Berkeley, CA 94720, United States
Department of Integrative Biology, University of California, 3060 Valley Life Sciences Building 3140, Berkeley, CA 94720, United States
Nielsen R.:
Department of Integrative Biology, University of California, 3060 Valley Life Sciences Building 3140, Berkeley, CA 94720, United States
Willerslev E.:
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
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