Assessment of thermal response, cardiorespiratory parameters and post-operative analgesia in dogs undergoing ovariohysterectomy with different combinations of epidural analgesia and isoflurane
Por:
Casas-Alvarado, Alejandro, Mota-Rojas, Daniel, Hernandez-avalos, Ismael, Martinez-Burnes, Julio, Rosas, Marcelino Evodio, Miranda-Cortes, Agatha, Dominguez-Oliva, Adriana, Mora-Medina, Patricia
Publicada:
1 ene 2023
Resumen:
This study aimed to evaluate the thermal response of the eyelids and
lacrimal gland of the left eye (LETG) through infrared thermography
(IRT), cardiorespiratory parameters, and their association with
nociception and pain in bitches undergoing elective ovariohysterectomy
(OVH) anesthetized with isoflurane and epidural analgesia. Twenty-one
healthy bitches of different breeds were randomized into three groups
receiving epidural blocks: GL (n=7), lidocaine (2 mg Kg-1); GLF (n=7),
lidocaine (2 mg Kg-1) and fentanyl (3 mu g Kg-1); and GLM (n=7),
lidocaine (2 mg Kg-1) with morphine (0.1 mg Kg-1). IRT and
cardiorespiratory parameters were evaluated at baseline (Ebasal), thirty
minutes before anesthetic premedication, and at different surgical
events: first incision (EInc), ligature and section of the left (ELoV),
and right (ERoV) ovarian pedicle, ligature, and re-section of the cervix
(EUt), and skin suture (ESut). The assessment of acute pain in the
immediate post-operative period was registered at E1h, E2h, and E3h
using IRT, the Dynamic Interactive Visual Analogic Scale (DIVAS), and
the University of Melbourne Pain Scale (UMPS) scales. The results showed
a statistically significant decrease in the lower eyelid surface
temperature (LELT) during EInc for GL (32.9 degrees C +/- 0.62), in
comparison to GLF (34.2 degrees C +/- 0.62) and GLM (35.3 degrees C +/-
0.62) (P = 0.006). Regarding LETG, a significant increase (P = 0.03) in
the IRT of Ebasal (36.8 degrees C +/- 0.63) and EInc (36.1 degrees C +/-
0.63) for GLM was observed in comparison to the thermographic values for
both perioperative events and groups. The GLM showed a significant
decrease in IRT values of ERoV at E3h in the upper and lower eyelids (P
= 0.03 and P = 0.01, respectively). A progressive and significant
reduction of the IRT values of LETG was also recorded in GLM, with
differences in ERoV (35.2 degrees C +/- 0.63) (P = 0.02) and E3h (35.3
degrees C +/- 0.63) (P = 0.01). The cardiovascular parameters (SAP, DAP,
and MAP) did not differ between treatments, but in GL, there was a
significant difference (P = 0.01) during EInc and ESut, compared to
Ebasal. In the body temperature, EInc and ESut gradually decreased in
all treatment groups (P = 0.01). In conclusion, hemodynamic and
cardiorespiratory stability was associated with IRT readings and the
absence of nociception. Changes in superficial temperature in the
immediate post-operative period were lessened using isoflurane and
epidural analgesia of lidocaine alone or in combination with pure
opioids. These findings were clinically validated to the DIVAS and UMPS
acute pain assessment scales.
Filiaciones:
Casas-Alvarado, Alejandro:
Univ Autonoma Metropolitana, Master Sci Program Maestria Ciencias Agr, Xochimilco Campus, Mexico City, Mexico
Mota-Rojas, Daniel:
DPAA Univ Autonoma Metropolita UAM, Neurophysiol Pain Behav & Assessment Welf Domest, Mexico City, Mexico
Hernandez-avalos, Ismael:
Univ Nacl Autcnoma Mexico, Fac Estudios Super Cuautitlan, Clin Pharmacol & Vet Anesthesia Biol Sci Dept, Behav 54714, Mexico
Univ Nacl Autcnoma Mexico, Fac Estudios Super Cuautitlan, Clin Pharmacol & Vet Anesthesia Biol Sci Dept, Assessment Welf 54714, Mexico
Martinez-Burnes, Julio:
Univ Autonoma Tamaulipas, Fac Med Vet & Zootecnia, Anim Hlth Grp, Tamaulipas 87000, Mexico
Rosas, Marcelino Evodio:
Univ Nacl Autonoma Mexico, Fac Estudios Super Cuautitlan, Biol Sci Dept Biostat, Cuautitlan 54714, Izcalli, Mexico
Miranda-Cortes, Agatha:
Univ Nacl Autcnoma Mexico, Fac Estudios Super Cuautitlan, Clin Pharmacol & Vet Anesthesia Biol Sci Dept, Behav 54714, Mexico
Univ Nacl Autcnoma Mexico, Fac Estudios Super Cuautitlan, Clin Pharmacol & Vet Anesthesia Biol Sci Dept, Assessment Welf 54714, Mexico
Dominguez-Oliva, Adriana:
DPAA Univ Autonoma Metropolita UAM, Neurophysiol Pain Behav & Assessment Welf Domest, Mexico City, Mexico
Mora-Medina, Patricia:
Univ Nacl Autonoma Mexico, Livestock Sci Dept, FESC, Cuautitlan 54714, Mexico
gold, Bronze
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