Usefulness of High-Resolution Computed Tomography in Early Diagnosis of Patients with Suspected COVID-19
Por:
Ronzon-Ronzon, Alma Angelica, Acevedo Salinas, Brenda Aida, Chapol, Jose Agustin Mata, Soto Valdez, Dalia Maria, Sanchez, Silvia Refugio, Martinez, Briceida Lopez, Parra-Ortega, Israel, Zurita-Cruz, Jessie
Publicada:
1 ene 2022
Resumen:
Background: Diagnosis of coronavirus disease 2019 (COVID-19) is mainly
based on molecular testing. General population studies have shown that
chest Computed Tomography (CT) can also be useful. Objective: The study
aims to examine the usefulness of high-resolution chest CT for early
diagnosis of patients with suspected COVID-19. Design And Setting: This
is a cross-sectional study from May 1, 2020, to August 31, 2021, at the
COVID Hospital, Mexico City. Methods: This study examined the clinical,
high-resolution chest CT imaging, and laboratory data of 160 patients
who were suspected to have COVID-19. Patients with positive Reverse
Transcription-Polymerase Chain Reaction (RT-PCR) testing and those with
negative RT-PCR testing but clinical data compatible with COVID-19 and
positive antibody testing were considered to have COVID-19 (positive).
Sensitivity and specificity of CT for diagnosis of COVID-19 were
calculated. p < 0.05 was considered significant. Results: Median age of
160 study patients was 58 years. The proportion of patients with
ground-glass pattern was significantly higher in patients with COVID-19
than in those without COVID (65.1% versus 0%; P = 0.005). COVID-19 was
ruled out in sixteen (11.1%). Only four of the 132 patients diagnosed
with COVID-19 (3.0%) did not show CT alterations (p < 0.001).
Sensitivity and specificity of CT for COVID-19 diagnosis were 96.7% and
42.8%, respectively. Conclusions: Chest CT can identify patients with
COVID-19, as characteristic disease patterns are observed on CT in the
early disease stage.
Filiaciones:
Ronzon-Ronzon, Alma Angelica:
Inst Mexicano Seguro Social, Radiol & Imaging Dept, Hosp Gen Zona 48, Mexico City, Mexico
Acevedo Salinas, Brenda Aida:
Inst Mexicano Seguro Social, Radiol & Imaging Dept, Hosp Gen Zona 48, Mexico City, Mexico
Chapol, Jose Agustin Mata:
Inst Mexicano Seguro Social, Coordinat Diagnost Assistants Dept, Hosp Gen Zona 48, Mexico City, Mexico
Soto Valdez, Dalia Maria:
Inst Mexicano Seguro Social, Radiol & Imaging Dept, Hosp Gen Zona 48, Mexico City, Mexico
Sanchez, Silvia Refugio:
Childrens Hosp Federico Gomez, Clin Lab Dept, Mexico City, Mexico
Martinez, Briceida Lopez:
Childrens Hosp Federico Gomez, Auxiliary Diagnost Dept, Mexico City, Mexico
Parra-Ortega, Israel:
Childrens Hosp Federico Gomez, Clin Lab Dept, Mexico City, Mexico
Zurita-Cruz, Jessie:
Univ Nacl Autonoma Mexico, Childrens Hosp Federico Gomez, Fac Med, Metab & Surg Clin Res Dept, Mexico City, Mexico
Calle Doctor Marquez 162 Col Doctores, Mexico City 06720, Mexico
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