Eficacia terapéutica de la buprenorfina para tratamiento de dolor agudo postoperatorio en cirugía torácica por toracoscopía
Por:
Posso-Sierra J.J., Carrillo-Torres O., Carrillo-Ruiz J.D., de La Vega-Montiel V., Gutiérrez-Román C.I.
Publicada:
1 ene 2021
Categoría:
Anesthesiology and pain medicine
Resumen:
Introduction: Posterior pain in thoracoscopy has an 80% incidence. These procedures are done under general anesthesia or sedoanalgesia. The buprenorphin in dosage of 4 µg/kg it’s the foundation for post-operatory pain treatment, nevertheless, smaller dosage can be sufficient. The objective of this study is to demonstrate that a dosage of buprenorphin from 1-3 µg/kg provides suitable analgesia with less side effects during post-operatory in patients who underwent thoracoscopic surgery. Material and methods: We conducted a double-blind, prospective, transversal study, in 48 patients which underwent a thoracoscopy divided in 3 groups: A (1 µg/kg), B (2 µg/kg), and C (3 µg/kg) treated with buprenorphin. We studied side effects, pain intensity (NVE), and sedative effect (RASS) from 0 to 120 minutes postanesthesia. Results: Dosage from 1 to 3 µg/kg did not generate side effects. The analgesia effect is higher with 2 µg/kg (p = 0.019) and 3 µg/kg (p = 0.045). Dosage of 1 and 2 µg/kg have lower sedative effect. Conclusion: The multimodal analgesia was diminished by 200% inmidiate postsurgical pain. Dosage from 2-3 µg/kg of buprenorphine are effective for pain control with less side effects and a superficial sedative effect during post-operatory. © 2021, Colegio Mexicano de Anestesiologia A.C.. All rights reserved.
Filiaciones:
Posso-Sierra J.J.:
Hospital General de México «Dr. Eduardo Liceaga», Mexico
Carrillo-Torres O.:
Hospital General de México «Dr. Eduardo Liceaga», Mexico
Carrillo-Ruiz J.D.:
Hospital General de México «Dr. Eduardo Liceaga», Mexico
de La Vega-Montiel V.:
Hospital General de México «Dr. Eduardo Liceaga», Mexico
Gutiérrez-Román C.I.:
Hospital General de México «Dr. Eduardo Liceaga», Mexico
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