Resistant starch consumption effects on glycemic control and glycemic variability in patients with type 2 diabetes: A randomized crossover study
Por:
Arias-Córdova Y., Ble-Castillo J.L., García-Vázquez C., Olvera-Hernández V., Ramos-García M., Navarrete-Cortes A., Jiménez-Domínguez G., Juárez-Rojop I.E., Tovilla-Zárate C.A., Martínez-López M.C., Méndez J.D.
Publicada:
1 ene 2021
Resumen:
We previously observed beneficial effects of native banana starch (NBS) with a high resistant starch (RS) content on glycemic response in lean and obese participants. Here, we aimed to determine the effects of NBS and high-amylose maize starch (HMS) on glycemic control (GC) and glycemic variability (GV) in patients with type 2 diabetes (T2D) when treatments were matched for digestible starch content. In a randomized, crossover study, continuous glucose monitoring (CGM) was performed in 17 participants (aged 28–65 years, BMI = 25 kg/m2, both genders) consuming HMS, NBS, or digestible maize starch (DMS) for 4 days. HMS and NBS induced an increase in 24 h mean blood glucose during days 2 to 4 (p < 0.05). CONGA, GRADE, and J-index values were higher in HMS compared with DMS only at day 4 (p < 0.05). Yet, NBS intake provoked a reduction in fasting glycemia changes from baseline compared with DMS (p = 0.0074). In conclusion, under the experimental conditions, RS from two sources did not improve GC or GV. Future longer studies are needed to determine whether these findings were affected by a different baseline microbiota or other environmental factors. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Filiaciones:
Arias-Córdova Y.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
Ble-Castillo J.L.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
García-Vázquez C.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
Olvera-Hernández V.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
Ramos-García M.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
Navarrete-Cortes A.:
Departamento de Medicina Interna, Hospital General de Zona No. 46, Instituto Mexicano del Seguro Social (IMSS), Villahermosa, 86060, Mexico
Jiménez-Domínguez G.:
Departamento de Medicina Interna, Hospital General de Zona No. 46, Instituto Mexicano del Seguro Social (IMSS), Villahermosa, 86060, Mexico
Juárez-Rojop I.E.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
Tovilla-Zárate C.A.:
División Académica Multidisciplinaria de Comalcalco (DAMC), Universidad Juárez Autónoma de Tabasco (UJAT), Comalcalco, 86650, Mexico
Martínez-López M.C.:
Centro de Investigación, División Académica de Ciencias de la Salud (DACS), Universidad Juárez Autónoma de Tabasco (UJAT), Villahermosa, 86150, Mexico
Méndez J.D.:
Hospital de Cardiología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, 06703, Mexico
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