Exploration of the Severity of Hepatic Encephalopathy Deterioration Process Through Dynamics of the EEG Band Power time series
Por:
Braverman-Jaiven D., Vargas D.S., Bojorges-Valdez E., Higuera-de la Tijera F., Pwrez-Hernandez J.L.
Publicada:
1 ene 2022
Resumen:
Cirrhosis is a liver disease that could impair the functionality of the neural system, limiting cognitive processes and reduce mobility, possibly because alterations on dynamics of neural communications. In this study the dynamics of band power fluctuations on ß and ? bands were studied on three groups: control, patients with cirrhosis and patients diagnosed with minimal hepatic encephalopathy. EEG signals were recorded on an oddball paradigm and analyzed to obtain the latency and amplitude of the P300 wave and Detrended Fluctuation Analysis (DFA) exponent values over ß and ? band power time series for each channel. As expected, the latency of the P300 wave was significantly different for control subjects (p< 10{-12}). Amplitudes were not as different, but they tend to decrease for cirrhosis and minimal hepatic encephalopathy groups. DFA exponent values also tends to describe a more regular process and seems to be related with presence of symptoms of hepatic encephalopathy. These subtle changes could be produced by the mechanisms of a mild neurological impairment and be used, if it is confirmed, as an index to evaluate such deterioration. © 2022 IEEE.
Filiaciones:
Braverman-Jaiven D.:
Universidad Iberoamericana Ciudad de México, Engineering Studies for Innovation Department, Mexico City, 01219, Mexico
Vargas D.S.:
Universidad Nacional Autónoma de México (UNAM), Research Department at Hospital General de México and Clinica de Transtornos del sueño Facultad de Medicina, Mexico city, 06720, Mexico
Bojorges-Valdez E.:
Universidad Iberoamericana Ciudad de México, Engineering Studies for Innovation Department, Mexico City, 01219, Mexico
Higuera-de la Tijera F.:
Gas-troenterology Service at Hospital General de México, Mexico city, 06720, Mexico
Pwrez-Hernandez J.L.:
Gas-troenterology Service at Hospital General de México, Mexico city, 06720, Mexico
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