Opportunistic infections in pediatric HIV infection: A study of 74 autopsy cases from Latin America


Por: Drut, R, Anderson, V, Greco, MA, Gutierrez, C, deLeonBojorge, B, Menezes, D, Peruga, A, Quijano, G, Ridaura, C, Siminovich, M, Mayoral, PV, Weissenbacher, M

Publicada: 1 jul 1997
Resumen:
The present report describes opportunistic infections found at 74 autopsies of pediatric HIV/AIDS patients performed at several hospitals in Latin American countries. Fungal infections were the most common (53 cases), Candida sp. (39.18%) and Pneumocystis carinii (20.27%) being the most frequently recognized. Other fungal diseases included histoplasmosis, aspergillosis, and cryptococcosis. Viral infections were present in 31 cases, 38.7% being due to cytomegalovirus. Other viruses recognized included herpes simplex and adenovirus. Additional opportunistic infections were due to Mycobacterium avium-intracellulare, toxoplasmosis, and tuberculosis. Nonspecific bacterial bronchopneumonia was present in II cases. Cytomegalovirus and P. carinii coinfection was the most common association found. In this series patients died at a younger age (72% at or younger than 2 year old) and there was a slightly higher number of cases of histoplasmosis and brain toxoplasmosis than in other previously published series of infants and children.

Filiaciones:
Drut, R:
 (Corresponding Author), HOSP NINOS DR RICARDO GUTIERREZ,SERV PATOL,RA-1900 LA PLATA,BUENOS AIRES,ARGENTINA
ISSN: 10771042





PEDIATRIC PATHOLOGY & LABORATORY MEDICINE
Editorial
TAYLOR & FRANCIS, 1900 FROST ROAD, SUITE 101, BRISTOL, PA 19007-1598
Tipo de documento: Article
Volumen: 17 Número: 4
Páginas: 569-576
WOS Id: A1997XF25800005
ID de PubMed: 9211549