Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation
Por:
Du, Kang, Pippel, Martin, Kneitz, Susanne, Feron, Romain, da Cruz, Irene, Winkler, Sylke, Wilde, Brigitta, Avila Luna, Edgar G., Myers, Gene, Guiguen, Yann, Macias Garcia, Constantino, Schartl, Manfred
Publicada:
1 mar 2022
Resumen:
Viviparity evolved independently about 150 times in vertebrates and more
than 20 times in fish. Several lineages added to the protection of the
embryo inside the body of the mother, the provisioning of nutrients, and
physiological exchange. This often led to the evolution of a placenta.
Among fish, one of the most complex systems serving the function of the
placenta is the embryonal trophotaenia/ovarian luminal epithelium of the
goodeid fishes. For a better understanding of this feature and others of
this group of fishes, high-quality genomic resources are essential. We
have sequenced the genome of the darkedged splitfin, Girardinichthys
multiradiatus. The assembly is chromosome level and includes the X and Y
Chromosomes. A large male-specific region on the Y was identified
covering 80% of Chromosome 20, allowing some first inferences on the
recent origin and a candidate male sex determining gene. Genome-wide
transcriptomics uncovered sex-specific differences in brain gene
expression with an enrichment for neurosteroidogenesis and testis genes
in males. The expression signatures of the splitfin embryonal and
maternal placenta showed overlap with homologous tissues including human
placenta, the ovarian follicle epithelium of matrotrophic poeciliid fish
species and the brood pouch epithelium of the seahorse. Our comparative
analyses on the evolution of embryonal and maternal placenta indicate
that the evolutionary novelty of maternal provisioning development
repeatedly made use of genes that already had the same function in other
tissues. In this way, preexisting modules are assembled and repurposed
to provide the molecular changes for this novel trait.
Filiaciones:
Du, Kang:
The Xiphophorus Genetic Stock Center, Department of Chemistry and Biochemistry, Texas State University, San Marcos, Texas 78666, USA
Pippel, Martin:
Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, 10307, Germany
Kneitz, Susanne:
Biochemistry and Cell Biology, Biocenter, University of Wuerzburg, Wuerzburg, 97074, Germany
Feron, Romain:
Department of Ecology and Evolution, University of Lausanne, Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland
LPGP, Rennes, 35000, France
da Cruz, Irene:
Developmental Biochemistry, Biocenter, University of Wuerzburg, Wuerzburg, 97074, Germany
Winkler, Sylke:
Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, 10307, Germany
Wilde, Brigitta:
Biochemistry and Cell Biology, Biocenter, University of Wuerzburg, Wuerzburg, 97074, Germany
Avila Luna, Edgar G.:
Instituto de Ecologia, Universidad Nacional Autónoma de México, Mexico City D.F.C.P. 04510, Mexico
Myers, Gene:
Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, 10307, Germany
Guiguen, Yann:
LPGP, Rennes, 35000, France
Macias Garcia, Constantino:
Instituto de Ecologia, Universidad Nacional Autónoma de México, Mexico City D.F.C.P. 04510, Mexico
Schartl, Manfred:
The Xiphophorus Genetic Stock Center, Department of Chemistry and Biochemistry, Texas State University, San Marcos, Texas 78666, USA
Developmental Biochemistry, Biocenter, University of Wuerzburg, Wuerzburg, 97074, Germany
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