Combined Bacterial and Herpes Simplex Virus Keratitis following Small-Incision Lenticule Extraction for the Correction of Myopia


Por: Ramirez-Miranda A., Mangwani-Mordani S., Quiroz-Casian N., Oliva-Bienzobas V., Cabral-Macias J., Navas A., Graue-Hernandez E.O.

Publicada: 1 ene 2021
Categoría: Ophthalmology

Resumen:
A 28-year-old male presented unilateral visual loss, intense ocular pain, redness and intraocular hypertension in his right eye 2 days after undergoing small-incision lenticule extraction (SMILE) in both eyes. Initial examination of the affected eye revealed the presence of white infiltrates within the corneal interface, as well as a central epithelial defect. The patient was diagnosed with infectious keratitis, posteriorly the eye was irrigated with balanced saline solution and treatment was initiated with hourly moxifloxacin 0.5%. Since this approach failed to resolve symptoms, a sample from the interface was obtained for PCR assay, which revealed the presence of herpes simplex virus DNA, confirming the cause of the infection. The patient was prescribed a regimen of oral acyclovir, topical ganciclovir and prednisolone. Clinical improvement following resolution of the epithelial defect was observed. Although rare, herpetic keratitis following SMILE is best managed via early diagnosis and initiation of appropriate anti-herpetic treatment. © 2021 S. Karger AG. All rights reserved.

Filiaciones:
Ramirez-Miranda A.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico

Mangwani-Mordani S.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico

Quiroz-Casian N.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico

Oliva-Bienzobas V.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico

Cabral-Macias J.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico

Navas A.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico

Graue-Hernandez E.O.:
 Department of Cornea and Refractive Surgery, Instituto de Oftalmología, Conde de Valenciana, Mexico City, Mexico
ISSN: 16632699
Editorial
Karger AG, ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND, Suiza
Tipo de documento: Article
Volumen: 12 Número: 1
Páginas: 227-231
WOS Id: 000647601700038
ID de PubMed: 33976687
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