Identification of high-risk COVID-19 patients using machine learning


Por: Quiroz-Juarez, Mario A., Torres-Gomez, Armando, Hoyo-Ulloa, Irma, de León-Montiel R.D.J., U'Ren, Alfred B.

Publicada: 20 sep 2021
Categoría: Multidisciplinary

Resumen:
The current COVID-19 public health crisis, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has produced a devastating toll both in terms of human life loss and economic disruption. In this paper we present a machine-learning algorithm capable of identifying whether a given patient (actually infected or suspected to be infected) is more likely to survive than to die, or vice-versa. We train this algorithm with historical data, including medical history, demographic data, as well as COVID-19-related information. This is extracted from a database of confirmed and suspected COVID-19 infections in Mexico, constituting the official COVID-19 data compiled and made publicly available by the Mexican Federal Government. We demonstrate that the proposed method can detect high-risk patients with high accuracy, in each of four identified clinical stages, thus improving hospital capacity planning and timely treatment. Furthermore, we show that our method can be extended to provide optimal estimators for hypothesis-testing techniques commonly-used in biological and medical statistics. We believe that our work could be of use in the context of the current pandemic in assisting medical professionals with real-time assessments so as to determine health care priorities.

Filiaciones:
Quiroz-Juarez, Mario A.:
 Departamento de Física, Universidad Autónoma Metropolitana Unidad Iztapalapa, Ciudad de México, Mexico

Torres-Gomez, Armando:
 ABC Medical Center, Ciudad de México, Mexico

Hoyo-Ulloa, Irma:
 ABC Medical Center, Ciudad de México, Mexico

de León-Montiel R.D.J.:
 Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de Mexico, Ciudad de Mexico, Mexico

U'Ren, Alfred B.:
 Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de Mexico, Ciudad de Mexico, Mexico
ISSN: 19326203





PLOS ONE
Editorial
PUBLIC LIBRARY SCIENCE, 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA, Estados Unidos America
Tipo de documento: Article
Volumen: 16 Número: 9
Páginas:
WOS Id: 000707078200023
ID de PubMed: 34543294
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