Working Memory in Children with Learning Disorders: An EEG Power Spectrum Analysis
Por:
Martinez-Briones, Benito J., Fernandez-Harmony, Thalia, Garofalo Gomez, Nicolas, Biscay-Lirio, Rolando J., Bosch-Bayard, Jorge
Publicada:
1 nov 2020
Categoría:
Neuroscience (miscellaneous)
Resumen:
Learning disorders (LDs) are diagnosed in children whose academic skills
of reading, writing or mathematics are impaired and lagging according to
their age, schooling and intelligence. Children with LDs experience
substantial working memory (WM) deficits, even more pronounced if more
than one of the academic skills is affected. We compared the
task-related electroencephalogram (EEG) power spectral density of
children with LDs (n = 23) with a control group of children with good
academic achievement (n = 22), during the performance of a WM task.
sLoreta was used to estimate the current distribution at the sources,
and 18 brain regions of interest (ROIs) were chosen with an extended
version of the eigenvector centrality mapping technique. In this way, we
lessened some drawbacks of the traditional EEG at the sensor space by an
analysis at the brain-sources level over data-driven selected ROIs.
Results: The LD group showed fewer correct responses in the WM task, an
overall slower EEG with more delta and theta activity, and less
high-frequency gamma activity in posterior areas. We explain these EEG
patterns in LD children as indices of an inefficient neural resource
management related with a delay in neural maturation.
Filiaciones:
Martinez-Briones, Benito J.:
Univ Nacl Autonoma Mexico, Inst Neurobiol, Dept Neurobiol Conductual & Cognit, Campus Juriquilla, Queretaro 76230, Mexico
Fernandez-Harmony, Thalia:
Univ Nacl Autonoma Mexico, Inst Neurobiol, Dept Neurobiol Conductual & Cognit, Campus Juriquilla, Queretaro 76230, Mexico
Garofalo Gomez, Nicolas:
Inst Neurol & Neurocirugia, Havana 10400, Cuba
Biscay-Lirio, Rolando J.:
Ctr Invest Matemat, Guanajuato 36000, Mexico
Bosch-Bayard, Jorge:
Univ Nacl Autonoma Mexico, Inst Neurobiol, Dept Neurobiol Conductual & Cognit, Campus Juriquilla, Queretaro 76230, Mexico
McGill Univ, Montreal Neurol Inst MNI, Ludmer Ctr Neuroinformat & Mental Hlth, McGill Ctr Integrat Neurosci MCIN, Montreal, PQ H3A 2B4, Canada
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