Regularized Estimation of Effective Scatterer Size and Acoustic Concentration Quantitative Ultrasound Parameters Using Dynamic Programming


Por: Jafarpisheh, Noushin, Rosado-Mendez, Ivan M., Hall, Timothy J., Rivaz, Hassan

Publicada: 1 ene 2020
Resumen:
The objective of quantitative ultrasound (QUS) is to characterize tissue microstructure by parametrizing backscattered radiofrequency (RF) signals from clinical ultrasound scanners. Herein, we develop a novel technique based on dynamic programming (DP) to simultaneously estimate the acoustic attenuation, the effective scatterer size (ESS), and the acoustic concentration (AC) from ultrasound backscattered power spectra. This is achieved through two different approaches: (1) using a Gaussian form factor (GFF) and (2) using a general form factor (gFF) that is more flexible than the Gaussian form factor but involves estimating more parameters. Both DP methods are compared to an adaptation of a previously proposed least-squares (LSQ) method. Simulation results show that in the GFF approach, the variance of DP is on average 88%, 75% and 32% lower than that of LSQ for the three estimated QUS parameters. The gFF approach also yields similar improvements. © 2020 IEEE.

Filiaciones:
Jafarpisheh, Noushin:
 Concordia University, Department of Electrical and Computer Engineering, Canada

Rosado-Mendez, Ivan M.:
 Universidad Nacional Autonoma de Mexico, Instituto de Fisica, Mexico City, Mexico

Hall, Timothy J.:
 University of Wisconsin-Madison, Department of Medical Physics, Madison, WI, United States

Rivaz, Hassan:
 Concordia University, Department of Electrical and Computer Engineering, Canada
ISSN: 05891019
Editorial
Alliance for Engineering in Medicine & Biology, Bethesda, MD, USA, 345 E 47TH ST, NEW YORK, NY 10017 USA, Estados Unidos America
Tipo de documento: Conference Paper
Volumen: 2020-July Número:
Páginas: 13-16
WOS Id: 000621592200004
ID de PubMed: 33017919