Müllerian anomalies prevalence diagnosed by hysteroscopy and laparoscopy in mexican infertile women: Results from a cohort study
Por:
Reyes-Muñoz E., Vitale S.G., Alvarado-Rosales D., Iyune-Cojab E., Vitagliano A., Lohmeyer F.M., Guevara-Gómez Y.P., Villarreal-Barranca A., Romo-Yañez J., Montoya-Estrada A., Morales-Hernández F.V., Aguayo-González P.
Publicada:
1 ene 2019
Categoría:
Clinical biochemistry
Resumen:
Background: To evaluate the prevalence of Müllerian anomalies (MAs) in a cohort of infertile Mexican women candidates for infertility treatments (intrauterine insemination or IVF (In vitro fertilization) cycles). Methods: We performed a retrospective observational study on a cohort of consecutive women, who underwent hysteroscopy and laparoscopy as part of the basic infertility workup from 2002 to 2014, at our center. Our aim was to calculate the prevalence of MAs and each subtype. Results: A total of 4005 women were included in the study. The MA prevalence was 4.4% (95% CI; 3.8-5.1; n = 177). Among women with MAs, the prevalence of different MA types was: Septate uterus 54.2% (n = 96), arcuate uterus 15.8% (n = 28), bicornuate uterus 10.7% (n = 19), unicornuate uterus 8.5% (n = 15), didelphys uterus 6.2% (n = 11) and hypoplasia/agenesis 3.4% (n = 6), unclassifiable 1.1% (n = 2). Women with MAs who achieved pregnancy were: 33.3% (n = 59). The MA associated with the highest pregnancy rate was septate uterus after hysteroscopic correction, at 38.5% (37/96). Conclusions: The prevalence of MAs among infertile Mexican women can be considered as low, but not negligible. The septate uterus is the most common MA in women with infertility. © 2019 by the authors.
Filiaciones:
Reyes-Muñoz E.:
Department of Gynecological and Perinatal Endocrinology, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Vitale S.G.:
Unit of Gynecology and Obstetrics, Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, 95123, Italy
Alvarado-Rosales D.:
Division of Human Reproduction, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Iyune-Cojab E.:
Division of Human Reproduction, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Vitagliano A.:
Unit of Gynecology and Obstetrics, Department OfWomen and Children's Health, University of Padua, Padua, 35122, Italy
Lohmeyer F.M.:
Scientific Directorate, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, 00168, Italy
Guevara-Gómez Y.P.:
Division of Human Reproduction, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Villarreal-Barranca A.:
Faculty of Medicine Universidad Veracruzana, Veracruz, 91090, Mexico
Romo-Yañez J.:
Department of Gynecological and Perinatal Endocrinology, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Montoya-Estrada A.:
Department of Gynecological and Perinatal Endocrinology, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Morales-Hernández F.V.:
Division of Human Reproduction, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
Aguayo-González P.:
Division of Human Reproduction, Instituto Nacional de Perinatología, Mexico City, 11000, Mexico
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